Fibrinolytic misc Flashcards
1
Q
What are the three fibrolynic drugs?
A
streptokinase, urokinase and tissue plasminogen activator
2
Q
Fibrinolytic drugs are used for
A
thrombotic disease like multiple pulmonary emboli
3
Q
Which fibrinolynic drug converts plasminogen to plasmin directly?
A
urokinase
4
Q
Which fibrinolynic forms an enzymatic complex?
A
streptokinase - this drug lyses the thrombin from within
5
Q
which plasmin is a human kinase?
A
urokinase-synthesized by the kidney
6
Q
t-PA is selective to
A
fibrin-bound plasminogen - not done systemically
7
Q
Which is the mutant form of T-PA?
A
tenecteplase
8
Q
Which t-PA is least fibrin-specific?
A
Reteplase
