Fibric acid derivatives Flashcards
1
Q
Net effect
A
decrease VLDL levels in plasma and lower triglycerides
2
Q
Fibrates MoA
A
ligands for PPaR - bind to it and induce lipolysis of VLDLs, also decreace intracellular lipolysis (like niacin)
3
Q
toxicity
A
gallstones, myopathy
4
Q
Which is the only fibrate with beneficial effects on CV?
A
gemfibrozil (decreases risk)
