fertilisation Flashcards
How can fertilisation of an egg alter the hormonal regulation of the menstrual cycle?
- Corpus luteum continues to secrete progesterone and oestrogen
- Endometrium is maintained which inhibits secretion of FSH from pituitary gland
- No more follicles in in the ovary begin to mature
why is a Large number of sperm required for fertilisation?
- High sperm mortality
- Some travel up the wrong fallopian tube to the one the egg is in
- Some must break down the corona radiata/acrosomal reaction
what is the first step of fertilisation?
Sperm moves through the cervix, up the uterus and into the fallopian tubes in search of a secondary oocyte
what is the second step of fertilisation?
Sperm’s acrosome releases enzymes which break down the zona pellucida
what is the third step of fertilisation?
Fertilisation membrane is formed when sperm enter oocyte-prevents more sperm entering
what is the fourth step of fertilisation?
Entrance of the sperm initiates secondary oocyte to complete 2nd meiotic division
what is the last step of fertilisation
Male and female pronuclei fuse and a zygote is formed
what happens to the zygote after fertilisation?
- Zygote divides to become ball of cells-morula
- Morula divides = blastocyst
- Occurs as embryo moves through fallopian tube towards uterus
- Blastocyst consists of inner cell mass
- Blastocyst implants into endometrium after 6-12 days
- Inner cell mass has developed into three primary germ layers after the third week