Female Genital System Flashcards
Ovary
- produces the ova and ovarian hormones
1. Estrogen
2. Progesterone
Ovary epithelium
- covered by a low cuboidal surface epithelium
Ovary Tunica Albuginea
- lies immediately below the surface epithelium
Ovary
- divided into the outer cortex and inner medulla
- > except in MARES
Mares
- their ovary is the exception and the areas are reversed
- > outer medulla and inner cortex
Ovary Outer Cortex
- contains numerous follicles and a corpora lutea
Ovary Inner Medulla
- characterized by blood vessels, nerves and lymphatics
Uterine Tube
- site of fertilization
Uterus
- site of implantation
Primordial Follicles
- composed of a primary oocyte surrounded by a simple squamous epithelium of follicular cells
Primary Follicles
- composed of a primary oocyte surrounded by a simple cuboidal epithelium of follicular cells
Secondary Follicles
- composed of a primary oocyte surrounded by a stratified epithelium termed granulosa cells which secrete zona pellucida
Granulosa Cells
- secrete the zona pellucida around the plasma membrane of primary oocytes
- stratified epithelium of polyhedral follicular cells
Theca Cells
- late secondary follicles
- begin to form around the granulosa cells
- a vascularized multilayer of spindle-shaped stromal cells
Tertiary, Mature or Graafian Follicles
- characterized by the development of the antrum
Antrum
- small fluid-filled clefts which join to form a large cavity among the granulosa cells
- contains liquor folliculi
Primary Oocyte
- immediately before or just after ovulation this completes the first meiotic division to give rise to a secondary oocyte and the first polar bodies
Cumulus oophorus
- antrum enlarges due to the accumulation of liquor folliculi, the oocyte is displaced and lies in a group of granulosa cells called this
Corona radiata
- the granulosa cells immediately surrounding the oocyte become radially
placed and are called this
Theca Interna
- have characteristic of steroid-secreting cells
Theca Externa
- consists of a thin layer of loose connective tissue with fibrocytes arranged concentrically
Ovulation
- rupture of the follicle and release of the oocyte
-
Ovulation
- caused by luteinizing hormone (LH) and increased pressure of the antral fluid
Follicular Atresia (degeneration)
- not all developing follicles terminate in ovulation
- many follicles undergo this
Corpus Atreticum
- atretic follicles are reabsorbed except for small fibrous tissue scar called this
- regressed without being ovulated
Ovaries of the Bitch and Queen
- there are interstitial endocrine cells
- arise from either:
- > epitheloid theca interna cells
- > hypertrophied granulosa cells of the atretic follicles
- contain lipid droplets
Corpus Hemorrhagicum
- the ruptured follicle after ovulation because of the blood in the antrum
Luteinization
- granulosa cells proliferate and transform into large luteal cells
- theca cells contribute to small luteal cells of the CL
Granulosa Cells
- large luteal cells
- steroid synthesizing cells
Theca Interna Cells
- small luteal cells
- more lipid and less steroid-synthesizing
Large and Small Luteal Cells
- both produce progesterone
Cows, mares and carnivores
- the yellow lipid pigment called lutein accumulates in the luteal cells
Ewe, Goats and Sows
- the yellow lipid pigment called lutein is absent
Corpus albicans
- If fertilization does not occur, the corpus luteum slowly degenerates and is replaced by connective tissue called this
- regressed CL of the estrous cycte
Mares
- Accessory corpus luteum is present
- > some primary/secondary follicle convert into additional CL for increased demand of progesterone
Order of Corpus Luteum
- Corpus Hemorrhagicum
- Corpus Luteum
- Corpus Albicans
- Corpus Atreticum
- Accessory Corpus Luteum
Corpus Luteum
- if fertilization does occur (pregnancy), this persists and is active for a variable amount of time
Rete ovarii
- embryonic remnants homologous to the rete testis
- prominent in carnivores and ruminants
Carnivores and ruminants
- rete ovarii is more prominent
Uterine Tube/Oviduct/Fallopian Tube
- Infundibulum
- Ampulla
- Isthmus
Infundibulum epithelium
- Pseudostratified Columnar epithelium
- > found only in this part of the oviduct
Ampulla and isthmus epithelium
- simple columnar epithelium
Uterus Components
- Bilateral Horns
- An unpaired body
- An unpaired neck, or cervix
Uterus Wall
- Endometrium
- Myometrium
- Perimetrium
Endometrium of the Uterine wall (uterus)
- mucosa-submucosa
- lined by simple columnar epithelium
Most species in the endometrium
- simple, or branched coiled tubular glands
- > except ruminants (caruncles)
Ruminants
- have caruncles which are nonglandular in the endometrium
Caruncles
- are nonglandular, circumscribed thickenings of the endometrium
- ruminants
Endometrium of the uterus wall in the Mare
- endometrial cups are present in early pregnancy due to densely packed uterine glands
Myometrium
- muscularis of the uterus wall
- consists of a thick circular inner layer and an outer longitudinal layer of smooth muscles
- a stratum vasculare occurs between the two layers of smooth muscles
Perimetrium
- serosa of the uterus wall
Cervix Epithelium
- simple columnar epithelium
Cervix
- highly folded mucosa-submucosa
- during pregnancy, the mucus thickens to form the cervical seal
- elastic fibers are predominent in the inner circular layer which are important in reestablishing cervical structure after parturition
Cervix
- mucigenous and goblet cells secrete mucus during estrus
Vagina Epithelium
- stratified squamous epithelium
Vagina in Bovine
- isolated foci of goblet cells are present in cranial part of vagina
Vagina propriasubmucosa
- dense irregular CT containing lymphatic nodules
Vagina Tunica Muscularis
- inner circular and outer longitudinal layer
Sows and Bitches
- the vagina has an additional thin layer of longitudinal muscle present inside the circular layer
Vestibular Wall
- similar to the caudal part of the vagina except for the presence of more subepithelial lymphatic nodules
Mares and Bitches Vestibule
- in the vestibule an erectile corpus cavernosum, termed bulbus vestibuli is present beneath the vestibular mucosa
Bulbus vestibuli
- an erectile corpus cavernosum
Clitoris
- homologous to the male penis
Vulva
- formed by the labia which are folds of the integuments
Estrous Cycle
- Proestrus
- Estrus
- Metestrus
- Diestrus
Proestrus
- is the period of follicular growth
- Endometrial proliferation and increased vascularization
Estrus
- ovulation occurs
- The endometrial proliferation and edema is more apparent
Metestrus
- development of the corpus luteum
- Endometrial gland hyperplasia
Diestrus
- is the phase of active corpus luteum under the influence of progesterone
- The endometrial glandular hyperplasia and secretion are maximum