February 9, 2016 - Respiratory Pathology Flashcards
Maximum Lung Development
Occurs around age 10
Acinus
A cluster of cells that resembles a berry.
In the lungs, this is in the respiratory bronchioles where they terminate in acini, which are many-lobed sacs containing groupings of alveoli.
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Type 1 Pneumocyte
Squamous cells (giving more suface area to each cell) and cover approximately 90-95% of the alveolar surface.
These cells are thin as they facililtate gas exchange between the alveoli and the blood in the capillaries.
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Emphysema
Abnormal permanent enlargement of the airspaces distal to the terminal bronchiole with alveolar wall destruction and without obvious fibrosis.
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Centriacinar Emphysema
Common among smokers, people with chronic bronchitis, and in the upper lobes.
(Smoking most often affects upper lobes)
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Panacinar Emphysema
Usually A1AT deficiency.
Made worse by smoking.
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Charcot-Leyden Crystals
Microscopic crystals found in people who have allergic diseases such as asthma, or found in parasitic infections such as parasitic pneumonia or ascariasis.
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They are indicitive of a disease involving eosiniphilic inflammation or proliferation.
Bronchiectasis
Permanent dilation of bronchi and bronchioles caused by destruction of the muscle and elastic tissue resulting from / associated with chronic necrotizing infections.
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Bronchopneumonia
Acute inflammation of the walls of the bronchioles.
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Empyema
A collection of pus in the plueral cavity.
Miliary Tuberculosis
Widespread disseminated Mycobacterium tuberculosis.
Characterized by tiny lesions
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Pneumoconiosis
An occupational lung disease and a restrictive lung disease caused by the inhalation of dust.
Deaths from silicosis, asbestosis, and coal.