Features of Renal Disorders

Question 1

Bartter syndrome - plasma renin

Answer 1

increased

Question 2

Bartter syndrome - aldosterone

Answer 2

increased

Question 3

Bartter syndrome - urine Ca

Answer 3

increased

Question 4

Liddle syndrome - BP

Answer 4

increased

Question 5

Liddle syndrome - plasma renin

Answer 5

decreased

Question 6

liddle syndrome - aldosterone

Answer 6

decreased

Question 7

Gitelman syndrome - plasma renin

Answer 7

increased

Question 8

Gitelman syndrome - aldosterone

Answer 8

increased

Question 9

Gitelman syndrome - serum Mg

Answer 9

decreased

Question 10

Gitelman syndrome - urine Ca

Answer 10

decreased

Question 11

SIADH - BP

Answer 11

normal or increased

Question 12

SIADH plasma renin

Answer 12

decreased

Question 13

SIADH aldosterone

Answer 13

decreased

Question 14

primary hyperaldosteronism - BP

Answer 14

increased

Question 15

primary hyperaldosteronism - plasma renin

Answer 15

decreased

Question 16

primary hyperaldosteronism - aldosterone

Answer 16

increased

Question 17

renin-secreting tumor - BP

Answer 17

increased

Question 18

renin-secreting tumor plasma renin

Answer 18

increased

Question 19

renin-secreting tumor aldosterone

Answer 19

increased

Question 20

Bartter syndrome

Answer 20

AR producing defective chloride channels -> defective sodium reabsorption in the thick ascending loop of Henle -> hypovolemia & activation of RAAS

Question 21

Bartter syndrome characterized

Answer 21

polyhydramnios, premature delivery, severe hypokalemia, hypochloremia, and metabolic alkalosis
BUN:Cr > 20 = hypovolemia
some have hyperuricemia

Question 22

Liddle syndrome

Answer 22

dysregulation of the ENaC channel in the collecting tubule -> increased sodium reabsorption and increased potassium secretion into urine