Congenital Diseases and Associated Clinical Findings

Question 1

congenital toxoplasmosis

Answer 1

intracranial calcifications (diffuse), hydrocephalus, chorioretinitis, hearing loss, neurodevelopmental delay

Question 2

congenital syphils

Answer 2

skeletal abnormalities (osteochondritis and periostitis), pseudoparalysis, persistent rhinitis, maculopapular rash (particularly on palms and soles or in diaper area)

Question 3

congenital rubella

Answer 3

cataracts, congenital glaucoma, pigmentary retinopathy, congenital heart disease (most commonly PDA or peripheral pulmonary artery stenosis), radiolucent bone disease, sensorineural hearing loss

Question 4

congenital cytomegalovirus

Answer 4

thrombocytopenia, intracranial calcifications, microcephaly, hepatosplenomegaly, sensorineural hearing loss

Question 5

herpes simplex virus (HSV) perinatally acquired HSV infection

Answer 5

thrombocytopenia, elevated liver transaminases, conjunctivitis or keratoconjunctivitis

Question 6

congenital varicella

Answer 6

cicatricial or vesicular skin lesions, microcephaly

Question 7

congenital Zika syndrome

Answer 7

microcephaly, intracranial calcifications, sensorineural hearing loss