extra micro questions Flashcards
these are NOT from past exams
The HSV virus reactivates via
a. retrograde flow
b. anterograde flow
b. anterograde flow
on a sensory neuron
Which of these is NOT a complication of chicken pox?
a. Pneumonia
b. Reyes syndrome
c. Guillain Barre syndrome
d. septic meningitis
e. transverse myelitis
f. cerebellar ataxi
g. encephalitis
d. septic meningitis
Aseptic meningitis is a complication, not septic meningitis
Zoster reactivation may result in facial paralysis if it occurs via
a. the trigeminal nerve
b. the cranial nerve VII and VIII
b. the cranial nerve VII and VIII
if the activation is via the trigeminal nerve, it may affect the eyes
Which these faces about Cytomegalovirus (CMV) is NOT true?
a. form multinucleated cells (owl eyes)
b. has a productive infection & a latent infection
c. has two serotypes
d. can spread via the placenta to the fetus
c. has two serotypes
it only has one
What type of malaria is a cofactor of Burkitt’s Lymphoma?
a. ovale malaria
b. falciparum malaria
c. vivax malaria
b. falciparum malaria
Which of the following does NOT cause croup?
a. influenza (an orthomyxovirus)
b. RSV (respiratory syncytial virus)
c. CMV (cytomegalovirus)
d. HMPV (Human metapneumovirus)
e. parainfluenza virus (a paramyxovirus)
c. CMV (cytomegalovirus)
Which of the following does not cause Herpetic Whitlow?
a. HSV 1
b. HSV 2
c. HSV 3
c. HSV 3
T/F: When the parotid glands of a mumps patient swell is when he can pass the virus
F: He can spread the virus 7 days before and after the swelling
What are the two liver enzymes you can test for if you think the patient has hepatitis?
Aspartate aminotransferase
Alaninie aminotransferase
How does the hepatitis virus travel from the GI to the liver?
Viremia
Which of the following can you get multiple times?
a. HAV
b. HBV
c. HEV
c. HEV
What is the only hepatitis virus that has dsDNA instead of ssRNA?
HBV
“Hepadna virus” is the best-known member is the hepatitis B viruses
Which if the following cannot be transmitted via breast feeding?
a. HBV
b. HCV
b. HCV
What does testing + for each of the following indicative of?
Hepatitis B surface antigen (HBsAg)
Hepatitis B surface antibody (HBsAb)
Hepatitis B e-antigen (HBeAg)
HBsAg- live virus in patient
HBsAb- recovered, immune, or vaccinated
HBeAg- tells you how active and contagious the virus is
HCV-specific IgG indicates
a. infectivity
b. exposure
c. immunity
b. exposure
A patient comes in passing loose fatty stools, what is the most likely diagnosis
a. entamoeba histolytica
b. gardia lamba
c. trichomonas vaginalis
b. gardia lamba
Which of the following is passed by trophozoite (the infective stage)?
a. entameoba histolytica
b. gardia lamba
c. trichomonas vaginalis
c. trichomonas vaginalis
Which of these has watery green diarrhea?
a. cyclospora
b. cryptosporidium
b. cryptosporidium
Which of these isn NOT a complication of aquairing toxoplasmosa during pregnancy?
a. Encephalitis
b. Abortion
c. Retinochoroiditis
d. Microcephaly
d. Microcephaly
Which of these malaria types does NOT cause latent infections via hypnozoites?
a. P. vivax
b. P. knowlesi
c. P. ovale
b. P. knowlesi
Why do you only find RBC’s in the ring stage in falciparum malaria?
The mature ones secrete antigens on the RBC surface that attach to capilaries and restrict them. So if you draw blood, you get the immature, ring stage RBC’s only.
Which of these Leshmaniasis stages is found inside the fly?
a. promastigotes
b. amastigotes
a. promastigotes
Which of the following is spread via phlembotomus?
a. malaria
b. leishmaniasis
c. african trypanosomiasis (African sleeping sickness)
b. leishmaniasis
malaria is spread by ANOPHELES
A patient acquires a life ling immunity after being infected with
a. cutaneous leishmaniasis
b. visceral leishmaniasis
a. cutaneous leishmaniasis
Which stage of Leishmaniasis is seen when you culture it NNN media?
a. promastigotes
b. amastigotes
a. promastigotes
Which stage of Leishmaniasis is seen when you smear it?
a. promastigotes
b. amastigotes
b. amastigotes
because they’re in the macrophage and don’t need the flagella
What can you conclude about patients that have a spreading cutaneous Leishmania infection?
They have low TH1 and high TH2 levels
they may have HIV, and thus a co-infection
Which leishmania strain is heat-sensitive?
a. L. major
b. L. mexicana
c. L. tropica
d. L. infantum
c. L. tropica
A patient is sleeping all the time, is disoriented and is malnutritioned. which of the following does he most likely have?
a. T.B. rhodesiense
b. T. cruzi
a. T.B. rhodesiense
sleeping sickness
How do you diagnose Strongyloides Stercoralis?
a. detecting the ova in the stool
b. detect the larvae in the stool
b. detect the larvae in the stool
How do you diagnose hookworms?
a. detecting the ova in the stool
b. detect the larvae in the stool
a. detecting the ova in the stool
hookworms= Necator Americanes and Ancylostoma dueodenale
Which of the following cause anemia?
a. Entrobius Vermicularis
b. Strongyloides Stercoralis
c. Necator Americanes and Ancylostoma dueodenale
d. Ascaris lumbricoides
c. Necator Americanes and Ancylostoma dueodenale
hookworms
Which of the following cause jaundice due to bile duct blockage?
a. Entrobius Vermicularis
b. Strongyloides Stercoralis
c. Necator Americanes and Ancylostoma dueodenale
d. Ascaris lumbricoides
d. Ascaris lumbricoides
What causes the double zone hemolysis of Clostridium perfringes?
a. alpha toxin
b. theta toxin
c. phospholipase C
d. catalase
b. theta toxin
C. tetani is sensative to
a. phospholipase C
b. tetanospasmin
c. tetanolysin
d. glutaraldehyde
e. aminoglycoside
d. glutaraldehyde
What is false about tetanus?
a. toxin-mediated illness
b. CNS affected via the blood and beta-motor fibers
c. causes rigid paralysis
d. prevented via DTP vaccine
e. can be caused by road traffic accidents
b. CNS affected via the blood and beta-motor fibers
it should be alpha, not beta motor fibers
Which of the Clostridium species is induced by antibiotics (ex/clindamycin)?
a. C. tetani
b. C. difficile
c. C. botulinum
b. C. difficile
T/F: if an infant with an HIV + mother tested positive, he has HIV
not necessarily, the child may have the HIV antibodies in his serum as a result of drinking the mom’s breast milk or by acquiring them during pregnancy or delivery
Which cell is destroyed by the HIV infection?
a. CD8 T cell
b. CD4 T cell
b. CD4 T cell
What is the confirmatory HIV test?
a. EIA test (enzyme immune assay)
b. western bolt test
b. western bolt test
Which of the following is NOT associated with Human T-Cell Lymphotropic Viruses (HTLV-l)?
a. Adult T-cell leukemia (ATL)
b. Atypical hairy cell leukemia (HCL)
c. Tropical spastic paraparesis (TSP)
d. HTLV-I–associated myelopathy (HAM)
b. Atypical hairy cell leukemia (HCL)
Which of the following is NOT associated with Human T-cell Leukemia Virus Type II (HTLV-II)?
a. Large granular lymphocytic leukemia (LGL)
b. Atypical hairy cell leukemia (HCL)
c. Tropical spastic paraparesis (TSP)
c. Tropical spastic paraparesis (TSP)
Histology lab finds clover leaf lymphocytes, which does the patient most likely have?
a. Large granular lymphocytic leukemia (LGL)
b. Adult T-cell leukemia (ATL)
c. Tropical spastic paraparesis (TSP)
b. Adult T-cell leukemia (ATL)
Which of the following viruses cause outbreaks of acute respiratory disease in military recruits?
a. adenovirus
b. orthopoxvirus
c. parapoxvirus
a. adenovirus
The rash of smallpox is
a. centrifugal
b. centripetal
a. centrifugal
What is the causative agent of smallpox?
Variola, an orthopoxvirus
HPV type 5 and 8 results in what disease?
a. Epidermodysplasia verruciformis (EV)
b. Laryngeal papilloma
c. Intraepithelial Neoplasia
a. Epidermodysplasia verruciformis (EV)
B is HPV 6&11
JC virus causes…
a. Merkel cell carcinoma (MCC)
b. Progressive multifocal leukoencephalopathy (PML)
b. Progressive multifocal leukoencephalopathy (PML)
BK virus causes a
in an asymptomatic polio infection, the virus is restricted to the
a. Blood
b. GI tract
c. Meninges
d. Brain
b. GI tract
Which polio paralysis affects the brainstem and causes muscle paralysis?
a. Bular paralysis
b. Spinal paralysis
c. Bulbospinal paralysis
a. Bular paralysis
What does mucocutaneous leishmaniasis destroy?
a. Connective tissue
b. Cartilage
c. Skin
b. Cartilage
A man presented with urethral discharge. What three species cause this?
Mycoplasma hominis (acellular discharge)
Neisseria gonorrhoeae (discharge has diplococci cells)
Chalmydia trachomatis (acellular discharge)
condyloma accuminata is caused by
a. adenovirus
b. CMV
c. HPV
c. HPV
condyloma accuminata = genetal warts
Which of the following tapeworms has hooks and hosts their cysts in pigs?
a. Taenia saginata
b. Taenia solium
b. Taenia solium
spreads by eating the cysts
Which of the following cause cysticercosis?
a. Taenia saginata
b. Taenia solium
c. Echinococcus granulosus
d. Echinococcus multilocularis
b. Taenia solium
Which of the following is most likely to cause anaphylactic shock?
a. Taenia saginata
b. Taenia solium
c. Echinococcus granulosus
d. Echinococcus multilocularis
c. Echinococcus granulosus
grows hydatid and they may rupture
Which of the following causes urinary schistosomiasis?
a. S mansoni
b. S japonicum
c. S hematobium
d. S mekongi
c. S hematobium
the rest are GI schisto
how is schistosomiasis transmitted?
a. fecal-oral route
b. through skin
c. sexually transmitted
b. through skin
Which of the following causes tropical pulmonary eosinophilia?
a. Wuchereria bancrofti
b. Onchocerca volvulus
c. Dracunculus medinensis
a. Wuchereria bancrofti
In which of these does the fly insert a larvae into the skin?
a. Wuchereria bancrofti
b. Onchocerca volvulus
b. Onchocerca volvulus
A= microfilarIae
Which of the following does NOT go through antigen variation to evade the immune system?
a. Trypanosoma Cruzi
b. Schistosomes
c. Plasmodium falciparum
d. Gardia lamblia
e. Nisseria gonorrhoeae
b. Schistosomes
Which of these release proteases to cleave IgG?
a. Trypanosoma Cruzi
b. Gardia lamblia
c. Plasmodium falciparum
d. Schistosomes
d. Schistosomes
For which of these is serology not useful?
a. Cryptosporidium
b. E. histolytica
c. Toxoplasmosis
a. Cryptosporidium
Gardia lambila & visceral leishmaniasis too
What is Chaga’s disease and what causes it?
A bug injects trypomastigotes and they travel to reticuloendothelial cells and smooth muscle cells to cause inflammation.
Caused by Trypanosoma Cruzi
What is the grouping of Neisseria spp.?
a. gram-positive cocci
b. gram-negative cocci
c. gram-positive bacilli
d. gram-negative bacilli
b. gram-negative cocci
Antitoxins are useless against…
a. cytotoxins
b. neurotoxins
c. endotoxins
d. enterotoxins
c. endotoxins
antitoxins are antibodies made to stop exotoxins; useless against endotoxins
Which of the following is novobiocin susceptible?
a. staph saprophyticus
b. staph epidermidis
b. staph epidermidis
Which of the following is optochin resistant and bile insoluble?
a. strept viridans
b. strept pneumoniae
a. strept viridans
Which of the following completely lyse RBC’s?
a. alpha hemolytic
b. beta hemolytic
c. gamma hemolytic
b. beta hemolytic
Which of the following causes tonsilitis?
a. beta-hemolytic group A
b. beta-hemolytic group B
c. beta-hemolytic group C
d. beta-hemolytic group F
c. beta-hemolytic group C (and group D)
Which of the following smells like caramel and causes abscesses?
a. beta-hemolytic group A
b. beta-hemolytic group B
c. beta-hemolytic group C
d. beta-hemolytic group F
d. beta-hemolytic group F
Which of the following has the Panton-Valentine Leucocidin to kill PMN (polymorphonuclear neutrophils)?
a. strept viridans
b. strept pneumoniae
c. staph aureus
b. staph epidermidis
c. staph aureus
What are complications of S. pyogenes?
Acute rheumatic fever after a throat infection
Acute glomerulonephritis after a throat or skin infection
Which of these is only available in the inferior mesenteric vein?
a. S. Hematobium
b. S. Mansoni
c. S. Japonicum
b. S. Mansoni
Which of these cause acute diarrhea after shellfish consumption?
a. V. cholera
b. V. parahemolyticus
c. V. vulnificus
c. V. vulnificus
parahemolyticus = explosive diarrhea
What type of shock does V. cholera cause?
a. cardiac shock
b. hypovolemic shock
c. anaphylactic shock
b. hypovolemic shock
diarrhea causes low volume
What is it called when Mycobacterium spreads to the lymph node and proliferates?
a. Ghon focus
b. Ghon complex (aka Primary complex)
b. Ghon complex
Ghon focus = only in the lung
Which of the following is used by mycobacterium for tubercle formation?
a. oxygen radical detoxification
b. antigen 85 complex
c. the high lipid in the cell wall
b. antigen 85 complex
Which of these has a type 4 pilus?
a. Neisseria gonorrhoeae
b. Neisseria meningitidis
b. Neisseria meningitidis
Which of these N. meningitidis serogroups does not have a vaccine?
a. A
b. C
c. W-135
d. Y
d. Y
serogroups X, Y, & Z are all rare and don’t have vaccines
Which of these is does a person coming back from Mecca most likely have?
a. Neisseria gonorrhoeae
b. Neisseria meningitidis
c. Moraxella Catarrhalis
b. Neisseria meningitidis
Which is the most infectious serotype of Legionella?
a. L. longbeachae
b. L. pneumophila
b. L. pneumophila
What color does Legionella appear under UV light?
a. gray-white
b. blue-green
c. blue-white
c. blue-white
How does the legionella enter a macrohage?
a. via a receptor
b. actin dependent entry
b. actin dependent entry
enters amoeba via receptor
what’s ppGpp and how does it relate to legionella?
ppGpp is Guanosine pentaphosphate, and it builds up when amino acids are low in a cell. So legionella uses the amino acids in a macrophage that it invades, and ppGpp is produced. The ppGpp regulates genes for amino acid uptake synthesis.
What does hyaluronidase do?
breaks down hyaluronic acid, which holds together connective tissue
Which of these does not cause infective endocarditis?
a. staph saprophyticus
b. staph epidermidis
c. staph aureus
a. staph saprophyticus
which of these has a hyaluronic acid capsule?
a. strept pneumoniae
b. Strept pyogenes
b. Strept pyogenes
pneumoniae has a polysaccharide capsule
What bacteria can be diagnosed by urea breath test?
helicobacter pylori
Why does Helicobacter pylori cause peptic ulcers?
the urase produces ammonia that acts to make ionic changes to the mucus layer. proteases then degrade that mucus.
what two stains are used for mycobacterium?
ziehl-neelsen stain
auramine stain
Which mycobacterium spp has the longest incubation period?
a. M. kansasi
b. M. avium-intracellulare
c. M. leprae
d. M. marinum
c. M. leprae
5-7 years incubation in young adults
Which of these N. meningitidis serogroups causes epidemic outbreaks?
a. A
b. B
c. C
d. W-135
b. B
Which of these N. meningitidis serogroups causes epidemic meningitis?
a. A
b. B
c. C
d. W-135
a. A (occurs in Africa)
How does Moraxella Catarrhalis initially attach to the nasopharynx?
a. slime
b. polysaccharide capsule
c. lipo-oligosaccharide
c. lipo-oligosaccharide
Which of the following legionella virulence factors stop lysosome fusion?
a. mip
b. dot/icm
c. mak
d. mil
e. pmi
b. dot/icm
defective organelle trafficking
Which of the following legionella virulence factors aids in infection?
a. mip
b. dot/icm
c. mak
d. mil
e. pmi
a. mip
macrophage infectivity promoter
What is pontiac fever and what causes it?
its a mild upper respiratory infection (lungs not involved) that resembles acute influenza, caused by legionella
Which of these methods does not kill legionella?
a. gamma rays treatment
b. monochloramine
c. UV light treatment
d. heating it to 60 degrees
a. gamma rays treatment
which of the following causes a dry and no painful penile ulcer?
a. Treponema pallidum
b. Haemophilus ducreyi
a. Treponema pallidum (causes syphilis)
Haemophilus ducreyi causes a wet and painful ulcer
What factors do Haemophilus species need to grow? Which agar can be used?
they need factors X and V, & NAD
chocolate agar is used to culture them
Which H. influenzae type is associated with invasive infections?
a. A
b. B
c. C
d. D
e. E
f. F
b. B
Which of the following exacerbates chronic obstructive pulmonary disease (COPD)?
a. invasive H. influenzae infections
b. non-invasive H. influenzae infections
b. non-invasive H. influenzae
Which of the following can lead to blindness?
a. Chlamydial opthalmia neonatorum
b. Adult inclusion conjunctivitis
c. Trachoma
c. Trachoma