2014 patho

Question 1

which of the following inflammatory diseases result in a large number of eosinophils?
A) Tuberculosis
B) Schistosomiasis
C) Acute appendicitis
D) Lobar pneumonia

Answer 1

B) Schistosomiasis

Question 2

what is the characteristic finding in granulomatous inflammation?
A) dense infiltrate of lymphocytes
B) Collection of pus
C) Group of epithelial cells
D) Group of epithelioid cells

Answer 2

D) Group of epithelioid cells

Question 3

what contributes to thrombosis (deep vein thrombosis)?
A) liver cirrhosis
B) prolonged immobility
C) nephrotic syndrome

Answer 3

B) Prolonged immobility

Question 4

What causes edema in acute inflammation?
A) neutrophils immigration
B) plasma leakage from capillary

Answer 4

B) plasma leakage from capillary

Question 5

A man presented with acute viral hepatitis, what is the most predominant cells in the liver?
A) eosinophils
B) lymphocyte
C) macrophages
D) neutrophils

Answer 5

B) lymphocyte

Question 6

Cancer cells are able to evade normal cell growth suppression. This is provided by which genetic deregulation?
A) p53 mutation
B) kras mutation
C) cMAC activation

Answer 6

A) p53 mutation

Question 7

The cell has got a limited number of replications; this is maintained by?
A) Telomere shortening
B) A tiny clock inside of the cell

Answer 7

A) Telomere shortening

Question 8

an ovarian tumor removed from a 20-year-old woman showed teeth, adipose tissue, hair, and sebaceous tissue.
What is the likely diagnosis?
A) hematoma
B) adenoma
C) teratoma
D) choristoma

Answer 8

C) teratoma

Question 9

what pigment is associated with aging?
A) lipofuscin
B) bilirubin
C) hemosiderin
D) melanin

Answer 9

A) lipofuscin

deposited in the heart of older patients

Question 10

a section from the uterine cervix shows a hyperchromatic, pleomorphic, nuclei with increased mitosis occupying the whole thickness of the squamous epithelium, what is it called?
A) metaplasia
B) anaplasia
C) carcinoma in situ
D) hyperplasia

Answer 10

C) carcinoma in situ

Question 11

What is the major component of granulation tissue?
A) foreign body giant cell
B) necrotic material
C) newly formed capillary
D) woven bone

Answer 11

C) newly formed capillary

Question 12

what is the most essential process for the development of an embryo in utero?
A) atrophy
B) hypertrophy
C) apoptosis
D) necrosis

Answer 12

C) apoptosis

Question 13

a 65 years old women has been on a long term hemodialysis due to chronic renal disease. She developed a joint problem that was diagnosed as amyloidosis. What is most likely the type?
A) b2 microglobulin amyloidosis
B) primary amyloidosis
C) AA amyloidosis
D) senile amyloidosis

Answer 13

A) b2 microglobulin amyloidosis

it’s hemodialysis-associated, patient comes in with chronic renal disease

Question 14

what is the function of apo-cII?
A) activates lipoprotein lipase
B) Activate LCAT Lecithin-Cholesterol Acyltransferase

Answer 14

A) activates lipoprotein lipase

Question 15

What is the definition of dystrophic calcification?

Answer 15

Local deposition of calcium in non-viable or dying tissue

Question 16

which organs are protected by auto regulatory mechanism at the early stage of shock?
A) Liver and gallbladder
B) stomach and pancreas
C) brain and heart
D) kidney and urinary bladder

Answer 16

C) brain and heart

Question 17

Sections of the liver from a diabetic women show normal architecture. Hepatocytes, however are distended from a large cytoplasmic vacuole. The liver function is normal. What is the finding?
A) it is a reversible cellular injury
B) it is a histological artifact
C) the finding is unrelated to diabetes
D) the large vacuole contains water

Answer 17

A) it is a reversible cellular injury

Question 18

Calculate the level of LDL cholesterol if:
total cholesterol = 6
HDL cholesterol = 0.8
Triglycerides level = 2.2
A) 4.2
B) 4.8
C) 5.4

Answer 18

A) 4.2

Question 19

What’s true about labile cells?
A) do not regenerate
B) always proliferate
C) have a slow growth rate

Answer 19

B) always proliferate

Question 20

Which of the following is considered as a major effect of acute ionizing radiation?
A) Activation of defense and repair mechanisms
B) Deactivation of defense and repair mechanisms

Answer 20

A) Activation of defense and repair mechanisms

Question 21

Which of the following is the cause of generalized edema that results from decreased oncotic pressure?
A) Congestive Heart failure
B) Nephrotic syndrome

Answer 21

B) Nephrotic syndrome

Question 22

A women underwent mastectomy to remove a mass in the breast. Upon examination of tissue removed from the axillary lymph nodes, unusual cell morphology was seen. What describes what was observed in the lymph nodes?
A) Neoplasia
B) Dysplasia

Answer 22

A) Neoplasia

Question 23

which of plasma protein is associated with pulmonary emphysema in young adults?
A) alpha 1 anti-trypsin
B) caeruloplasmin
C) Beta 2 microglobulin

Answer 23

A) alpha 1 anti-trypsin

Question 24

What is genomic medicine?

Answer 24

A new discipline that utilizes nucleic acid sequencing information to predict, diagnose and personalize medical treatment.

Question 25

Accumulation of excessive amount of collagen is?
A) exuberant granulation
B) keloid
C) aggressive fibromatoses

Answer 25

B) keloid