Exercise and the immune system 2 Flashcards
Issues with the animal studies looking at effect of exercise on immune response?
They cant control for the stress response and other factors that arise in the animals as a result of the studies
Why is salivary IgA used to observe the effect of exercise on immune function?
It is non invasive
What was discovered regarding the Tomasi skiers IgA study?
Salivary IgA was reduced by 20% in cross country skiers after 2-3hrs of exercise
What was the conclusion of the skiing study?
A temporary antibody deficiency in saliva might lead to an increase in susceptibility to viral and bacterial infections following strenuous exercise
What was seen immediately post race in salivary IgA in the SA marathon study?
A sharp decrease in salivary IgA
Was there a correlation between URTI symptoms and salivary IgA conc?
No
What do most studies say about the effect of exercise on salivary IgA?
Exercise doesnt cause a decrease in IgA secretion
What happens to the levels of salivary IgA levels in the absence of exercise?
It is very variable
What are some factors that affect salivary IgA?
Diet, psychological stress, oral disease, menstrual cycle, medications, oral hygiene
What is the blood immune response during exercise?
Increased levels of blood lymphocytes
What is the blood immune response after exercise?
Decreased levels of blood lymphocytes (to lower levels than b4 exercise)
Biphasic response of blood lymphocytes during exercise?
Increases during, sharply decreases after
Which immune cell increases the most during exercise?
NK cells
Which immune cell increases by the lowest amount during exercise?
CD4+ T cells
Which type of immune cells increase the most during exercise?
cells with the greatest cytotoxic potential
