Exam Two: Inflammation

Question 1

What are the classical definitions of inflammation?

Answer 1

1. Heat and Rashes
2. Swelling
3. Pain

Question 2

In inflammation what causes Heat and Redness and what does it mean?

Answer 2

Vasodilation- widening of the blood vessels

Heat and Redness are a side-effect of increased blood flow

Question 3

What is the technical term for Swelling?

Answer 3

Oedema

Question 4

What causes oedema in inflammation?

Answer 4

Leaky blood vessels that allow leukocytes to cross into the tissue.

Question 5

Pain is what to the body?

Answer 5

A warning signal that there is a problem

Question 6

What is the technical definition for inflammation?

Answer 6

Recruitment of cells that cause damage(injury) as a side effect of fighting infection.

Question 7

Is inflammation a long or short term response?

Answer 7

It is meant to be a short term response

Question 8

Why must a inflammation response be limited?

Answer 8

Can cause tissue damage that becomes pathological

Question 9

What is an inflammatory disease?

Answer 9

Result of a persistent infection or injury that cannot be resolved

Question 10

Match the disorder with the organ it effects:

1. Nephritis
2. Arthritis
3. Dermatitis
4. Hapatitis
5. Vasculitis
6. Bronchitis

Answer 10

1. Kidney
2. Joints
3. Skin
4. Liver
5. Blood Vessels
6. Airway of the lung

Question 11

Why can inflammation be cause by an infection and/or injury?

Answer 11

They come as a package deal. Infection is the innate immune response and injury is the wound healing response.

Question 12

What is Thrombosis?

Answer 12

It is a wound healing response of blood clotting

Question 13

What is fibrosis?

Answer 13

condition where the process of damaged matrix is degraded and fibrin fills in the gaps is uncontrolled. This leads to scarring that destroys tissue

Question 14

Are the classic symptoms of inflammation observed in chronic conditions?

Answer 14

No

Question 15

What is Pulmonary Emphysema

Answer 15

Damage to tissue caused by persistent inflammatory response without an infection

Question 16

What is Septic Shock

Answer 16

Inflammatory disease that occurs all throughout the body instead of local

Question 17

What is Atherosclerosis?

Answer 17

Inflammatory disease that was though to be non inflammatory

Question 18

What is Autoinflammatory Disorders?

Answer 18

Genetically inherited disorder

Give rise to the symptoms of severe infection even when there isn’t one

Question 19

What does Systemic represent in light of immune response?

Answer 19

Means the response occurs throughout the body

Question 20

What are Atherosclerotic Plaques made of?

Answer 20

Plaques are caused by the recruitment of monocytes that cannot pass through the artery

Question 21

What is an Atherosclerotic Plaque

Answer 21

Sites of leukocyte recruitment and fibrosis that result in tissue damage and is a form of chronic inflammation

Question 22

What is an Autoinflammatory Disease?

Answer 22

Inappropriate expression of chemical messenger molecules called primary cytokines

Question 23

What is the function of a cytokine?

Answer 23

They initiate and amplify the inflammatory response