Exam 3: Autoimmunity

Question 1

Occurs when the adaptive immune system destroys normal healthy tissue:

Answer 1

Autoimmunity

Question 2

Autoantigens:

Answer 2

Self-antigens that are inappropriately recognized by antigen receptors.

Question 3

Do not have a nucleus and lack regulatory factors and other immune protective mechanisms

Answer 3

Red blood cells and Platelets

Question 4

Autoimmune Hemolytic Anemia:

Answer 4

Red Blood Cells are destroyed

Question 5

Autoimmune Thrombocytopenic purpura:

Answer 5

Platelets are destroyed

Question 6

What is the main mechanism in the destruction of red blood cells in hemolytic anemia

Answer 6

Macrophage phagocytosis in the spleen

Question 7

What disease is an example of epitope spreading?

Answer 7

The production of DNA antibodies in Lupus

Question 8

Pemphigus Vulgaris:

Answer 8

Severe blistering of the skin and mucosa membrane

Question 9

How can autoantibodies be removed from a baby?

Answer 9

Plasmapheresis, which is exchanging the infants blood or plasma.

Question 10

Autoimmune diseases that involve autoantibodies and self-reactive T cells?

Answer 10

MS (Multiple Sclerosis)
Rheumatoid Arthritis
Type I diabetes