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Immunology > Exam Two: Cytokines > Flashcards

Exam Two: Cytokines Flashcards

1
Q

What is the job of Chemical Messengers aka Signals?

A

They perform the job of relaying messages between cells. (example Insulin and Adrenaline)

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2
Q

What is the function of a cytokine?

A

to allow different immune cells to communicate with one another.

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3
Q

What is the function of a signal transduction pathway?

A

To induce the correct response from the message

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4
Q

What is an immune mediator?

A

A chemical signal in immunity ( protein, lipid, or carbohydrates)

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5
Q

What is the formal definition of a cytokine?

A

protein that act as chemical messengers in the immune system that have specific receptors

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6
Q

What is the formal definition of Chemokines?

A

They are a subset of Cytokines, that function as a chemoattractant. `

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7
Q

What is the function of a chemoattractant?

A

They attract white blood cells to a particular location

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8
Q

List the Primary Cytokines:

A

IL -1
IL-6
TNF

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9
Q

List the Cytokines associated with cell division:

A

IL- 2 and IL 3

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10
Q

What is the function of Interleukins?

A

They send messages between white blood cells

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11
Q

What is the function of Interferons?

A

Produced by virus-infected cells that interfere with infection of other cells = limit the spread of viruses

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12
Q

What is the Function of Tumor necrosis factor and Transforming growth factor beta?

A

Molecules that act on cancer cells but also play a essential role in the immune system.

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13
Q

TH1 T cell subset is induced by which Interferon?

A

Induced by Interferon gamma (y)

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14
Q

TH2 subset is induced by which Interleukins?

A

Interleukin-4 and 5

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15
Q

TReg cells are induced by what?

A

It induced by TGFB and IL-10

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16
Q

What is Interleukin-2

A

General T cell growth factor

needed for clonal amplification

17
Q

What is the type of response in the innate immune system that responds to viral infections?

A

The Interferon Response

18
Q

Production of Type I interferons and NK cells is involved in which response of the immune system?

A

The innate Immune response

19
Q

What Receptor recognizes Viral RNA in the cell?

A

RIG - 1 which stimulates cytokine and interferon production

Recognize invading germs

20
Q

What is the Febrile Response?

A

A fever, which is just an increase in body temperature

Immunology (18 decks)

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