Exam 4: Endocrine System Flashcards
Endocrine gland
-secretes hormones into bloodstream.
Hormone
- chemical messenger that regulates activity of other body cells.
- hormone levles constantly adjusted by feedback loops.
Negative Feedback Loop
- a stimulus causes an endocrine organ to release hormones
- the hormone helps bring the body back to homeostasis
- once homestasis is achieved, the hormone release stops
Endocrine System
- all endocrine glands in body
- overseen by hypothamus
Hypothalamus’ Control (3 Ways)
- produces regulatory hormones that stimulate or inhibit anterior pituitary hormone secretion
- produces ADH and oxytocin and are stored in posterior pituitary
- oversees ANS, stimulates hormone secretion of adrenal medulla via sympathetic innervation
Pituitary Gland
- connected to hypothalums via infundibulum
- split into anterior and posterior
Posterior Pituitary
- axons from hypothalamus cells
- stores two hormones produced by hypothalamus: oxytocin and ADH
Oxytocin
- cuddling/trust hormone
- stimulates uterine contractions/ induces labor (menstrual cramps)
- stimulates breast milk release in response to suckling infant
- males: stimulates smooth muscle contraction in reproductive tract
ADH
- diuresis = urine production
- inhibits urine formation/production
- concentrates urine
- ADH targets the kidneys and blood vessels
- secreted when dehydrated
- tells kidneys to concentrate urine by reabsorbing more water
- blood vessels constrict to increase blood pressure
Anterior Pituitary
- VP of endocrine system, controlled by hypothalamus
- controls growth hormone (GH), thyroid stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle stimulating hormone (FSH), luteinizing hormone (LH), and prolactin (PRL)
Growth Hormone (GH)
- stimulates cell growth and mitosis in most cells
- especially affects skeletal and muscular systems, and adipose tissue
- anterior pituitary–>secretes GH–>targets muscle, bone, fat
Thyroid Stimulating Hormone (TSH)
- targets thyroid gland
- stimulates thyroid to produce/release its own hormones
- anterior pituitary–>secretes TSH–>targets thyroid gland–>secretes TH
Adrenocorticotropic Hormone (ACTH)
- target organ: adrenal cortex
- stimulates adrenal cortex to release its hormones
- anterior pituitary–>secretes ACT–>adrenal cortex–>secretes hormones
Follicle Stimulation Hormone (FSH)
- target organs: ovaries and testes
- anterior pituitary–>secretes FSH–>targets onads
Luteinizing Hormone (LH)
- target organs: ovaries and testes
- anterior pituitary–>secretes LH–>targets gonads
Prolactin (PRL)
- target organs: mammary glands
- stimulates breast milk production
- anterior pituitary–>secretes PRL–>targets mammary glands
Thyroid Gland
- anterior to trachea and inferior to larynx
- secretes thyroid hormone (TH) anad calcitonin
Thyroid Hormone (TH)
- increases cellular activity (metabolic rate) in most cells of body
- hypothalamus–>anterior pituitary–>secretes TSH–>targets thyroid gland–>secretes TH
Calcitonin
- encourages deposition of calcium from bloodstream into bone tissue
- secreted when blood calcium levels are high
- lowers blood calcium levels
- increases bone deposition
Parathyroid Glands
- 4 tiny oval masses behind thyroid
- secrete parathyroid hormone (PTH) when blood calcium levels are low
- increases blood calcium levels
- stimulates osteoclasts to resorb bone, release calcium into blood
Adrenal Glands
- superior to kidneys
- have outer cortex and inner medulla
Adrenal Cortex
- releases corticosteroids in response to ACTH
- one group of these steroids: controls balance of sodium (Na+) and potassium (K+) ions in body fluids (regulates salt)
- another (2nd) group of steroids stimulates metabolism of glucose from fats and proteins (regulates blood sugar levels)
- another (3rd) group of these steroids: secretes small amounts of androgens (male sex hormones)
- in females, some androgens are converted to estrogen (regulates sex)
Adrenal Medulla
- stimulated by sympathetic division of ANS
- secretes epinephrine and norepinephrine
- prolongs “fight or fligh” response by sympathetic innervation
- hypothalamus–>sympathetic innervation–>adrenal medulla–>epinephrine and norepinephrine
Pancreas
- has both exocrine and endocrine functions
- exocrine functions were discussed w/digestive system
Pancreatic Islets
- produces hormones
- Insulin and glucagon
- helps convert some glucose into glycogen (a carbohydrate)
Insulin
- lowers blood sugar (glucose) levels, enhances cells ability to pick up glucose
- secreted when you eat a meal
Glucagon
- raises blood sugar levels
- breaks down glycogen into glucose
- secreted when you haven’t eaten in a while
Gonads
- ovaries produce estrogen and progesterone
- testes produce androgens (especially testosterone)