[Exam 4] Chapter 51 - Diabetes Flashcards
Diabetes: What is this?
Group of metabolic diseases characterized by increased levels of glucose in blood
Diabetes: What can cause this to occur?
Defects in insulin secretion, insulin is not as effective anymore, or combination of both.
Diabetes: What are the different types?
Type 1 and Type 2
Diabetes: What does Type 1 involve?
Beta Cells in the pancreas are destroyed.
Diabetes: What can cause Type 1 DM?
Can be genetic or autoimmune related.
Diabetes: What happens when beta cells are desroyed?
Insulin production is reduced
Diabetes: What are Type 1 Diabetics treated with?
Insulin
Diabetes: What does insulin bind to?
REceptors on the cells and see an increase amount of glucose in the blood
Diabetes: What is basically occuring in Type 1 DM?
Body is not producing enough insulin to do its job
Diabetes: What is Type 2 DM?
Pancreas produces enough insulin, but cells aren’t responsive to insulin
Diabetes: What effect does insulin have on cells?
Is the key to cells. Opens it up so glucose can go from the blood into the cells; that is the energy.
Diabetes: insulin is secreted by what?
Beta cells in the pancreas
Diabetes: What is the purpose of glucose?
It gives energy to the muscle, liver, fat cells
Diabetes: What are some of the different actions of insulin?
Transport and metabolizes glucose for energy, stimulates storage of glucose in liver and muscle.
Tells liver to stop releasing glucose
Enhances storage of dietary fat and adipose tissue
Accelerates transport of amino acids into cells
Diabetes: Glucose is stored in the liver as what
Glycogen.
Diabetes: Insulin inhibits the breakdown of what
Stored glucose, protein, and fat. Important to know when body cannot get energy from glucose, it will start to break this down
Diabetes: What happens if the liver needs to release glycogen from liver?
Will go through glycogenolysis to become glucose. Amino acids can also be converted during this step to become glucose
Diabetes: Where does energy come from when someone is in DKA and body doesn’t have enough energy?
It’ll start breaking down fatty acids and goes through ketogenesis. Releases ketone bodies to be used for body, heart, and brain.
Diabetes: Insulin is basically what?
The key that opens up the pathway , opens the door for glucose to enter the cell.
Diabetes: Risk factors for diabetes?
Family Hx
Obesity
Hypertension
Elevated Triglyceride Levels
Diabetes: Diabetes is the leading cause of what?
Non-traumatic amputations
Blindness
ESRD
Diabetes: What is the difference between Type 1DM and Type 2 DM?
Type 1: Pancreas fails to produce insulin
Type 2: Cells fail to respond to insulin correctly
Diabetes: What is having Type 1 DM bad?
Since pancreas isn’t producing insulin, you have glucose floating around in bloodstream. Can’t get into cells
DKA: This only occurs with who?
Those with Type 1 DM
DKA: What occurs in DKA?
There is not enough insulin this results in hyperglycemia, dehydration, and electrolyte loss along with acidosis
DKA: What do kidneys do here?
they try to excrete the excess glucose , and that is why there is dehydration and electrolyte imbalance
DKA: Why does the body go into acidosis?
Because the body is trying to break down fats for energy causing ketone bodies which leads to acidosis.
DKA: Important for Diabetics to follow Sick Day Rules, which include what?
Take insulin as usual
Test glucose/ketones every 3-4 hours
Report elevated glucose
Take supplemental glucose ever 3-4 hours as needed
Sub soft foods if needed
Take liquids every 30- 1 hour to prevent dehydration
DKA: What are the three main causes of this?
Either decreased or missed doses of insulin
Illness/infection
Undiagnosed/untreated diabetes.
DKA: What happens when patients are sick and they don’t eat enough food?
It could throw them into DKA
DKA: How do you prevent this when sick?
Continue to take insulin
Check glucose levels/ketones every 3-4 hours
Be in contact with provider.
Sub foods for soft foods. Stick to meal plan.
DKA - CMs: What are the first three main ones we may see?
Polyuri, Polydipsia, Fatigue
DKA - CMs: What are some other signs that they may have?
Hypotension due to volume depletion
Acidotic
Fruity Breath
DKA - CMs: What GI symptoms may they have?
Anorexia, N/V, abdominal pain
DKA - CMs: What is the hallmark sign of this?
Fruity breath due to buildup of ketones
DKA - CMs: How will their respiration’s be?
Kussmaul Respirations (deep, rapid breathing). they are in metabolic acidosis and are trying to breathe off the CO2.
DKA - CMs: Mental status can vary how?
Some can be in coma, or some can be alert.
DKA - CMs: Assessment will focus on what?
The clinical manifestations. Assessing for dehydration, blood pressure, gi status, fruity breath, kuzzmal breathing.
DKA - Diagnostics: What will their glucose level be at?
300-800.