[Exam 1] Chapter 57: Management of Patients with Female Reproductive Disorders Flashcards
Ovary Cancer: Why is this difficult to find?
They are usually deep in the pelvis and no early screening mechanism exists.
Ovary Cancer - Epidemiology: Median age for this?
Most cases diagnosed by 60.
Ovary Cancer - Epidemiology: Most significant risk factor?
Family history.
Ovary Cancer - Epidemiology: Mutation occurs on wha gene?
GRCA1 and sometimes BRCA2 gene.
Ovary Cancer - Epidemiology: Lifetime risk of developing ovarian cancer has been shown to be derecrease by one half with what
long-term suppression (>5 years) of ovulation through use of oral contraceptives
Ovary Cancer - Patho: What are germ cell tumors?
Germ cell tumors, which arise from cells that produce eggs and are the most common in those younger than 20.
Ovary Cancer - Patho: What are stromal; cell tumors?
Arise in CT cells that produce hormones
Ovary Cancer - Patho: What are epithelial tumors?
It originates from the outer surface of the ovary.
Ovary Cancer - Patho: Most ovarian cancers are of what origin?
Epithelial.
Ovary Cancer - Patho: What is closely related to this ?
Primary peritoneal carcinoma.
Ovary Cancer - Patho: What is extraovarian primary peritoneal carcinoma?
Resembles ovarian cancer histologically and can occur in women with/without ovaries.
Ovary Cancer - CMs: Symptoms of this include?
Increased abdominal girth, pelvic pressure, bloating, back pain, constipation, abdominal pain, urinary urgency, flatulence, and increased waist size.
Ovary Cancer - CMs: Most common sign?
Enlargement of the abdomen from an accumulation of fluid
Ovary Cancer - CMs: What would alert nurse to possibility of early ovarian malignancy?
Vague, undiagnosed persistent GI symptoms
Ovary Cancer - CMs: Palpable ovary in woman who has gone through menopause must do what
must be evaluated because they are normally smaller and less palpable after menopause
Ovary Cancer - Assessment/Diagnostic: Which diagnostic tests are not definitivve?
Pelvic Exam, and Pelvic Imaging
Ovary Cancer - Assessment/Diagnostic: Classified as benign when
There is no proliferation or invasion,
Ovary Cancer - Assessment/Diagnostic: Classified as borderline when
if there is proliferation but no invasion
Ovary Cancer - Assessment/Diagnostic: classified as malignant when
if there is invasion
Ovary Cancer - Assessment/Diagnostic: Diagnostic tests may include what
MRI scan, transvaginal and pelvic ultrasound, chest x-rays, and blood test for CA-125
Ovary Cancer - Surgical Mx: What is the basis of treatment?
Surgical staging, exploration, and reduction of tumor mass. Surgical removal best choice.
Ovary Cancer - Surgical Mx: Treatment likely involves what
total abdominal hysterectomy with removal of fallopian tubes and ovarianes and possibly the omentum , tumor debulking, and pelic lymph node sampling.
Ovary Cancer - Surgical Mx: Postop management includes
taxanes or platinum-based chemotherapy
Ovary Cancer - Surgical Mx: Treatment forr someone with a borderline tumor?
Younger, and conseravitive approach used. Affected ovary removed but uterus and other ovary may remain in place
Ovary Cancer - Pharmacologic Therapy: Chemo is usually administered using which type?
Combo of platinum and taxane agents. Paclitaxel and Carboplatin are most often used bc of manageable toxicity.
Ovary Cancer - Pharmacologic Therapy: What SE may occur with Paclitaxel and Carboplatin?
Leukopenia, neurotoxicity, and fever.
Ovary Cancer - Pharmacologic Therapy: What do patients taking Paclitaxel with leukopenia need to take
granulocyte colony-stimulating factors.
Ovary Cancer - Pharmacologic Therapy: What are some severe cardiac reactions of paclitaxel?
Hypotension, dyspnea, and angioedema and urticaria.
Ovary Cancer - Pharmacologic Therapy: Carboplatin may be used in initial tx but used in caution with what patient
those with renal impairment. Six cycles are given.
Ovary Cancer - Pharmacologic Therapy: Positive clinical response to carboplatin
Normalization of tumor marker CA-125. negative CT results and a normal physical and gynecologic exam
Ovary Cancer - Pharmacologic Therapy: What does Liposomal therapy allow for?
Delivery of chemo in a liposome, which allows highest dose of chemotherapy to tumor target with a reduction in adverse effects. Are nontoxic, biodegrable, easily available and inexpensive.
Ovary Cancer - Pharmacologic Therapy: What drug used with liposomal therapy?
Doxorubicin (Doxil) lessens incidence of N/V, and Alopecia. Must b monitored for bone marrow suppression.
Ovary Cancer - Pharmacologic Therapy: Intraperitoneal chemotherapy is reserved for who
women with good kidney function because its more toxic and side effects are more severe
Ovary Cancer - Pharmacologic Therapy: For those with recurrence, treatment is directed toward?
Control of cancer, maintenance of quality of life, and palliation.
Ovary Cancer - Nursing Mx: Those involves what
Those related to patients tx plan, which may include suergery, chemotherapy, palliative care or combo of them.
Ovary Cancer - Nursing Mx: Nursing interventions are pelvic surgery?
Similar to those after other abdominal surgeries.
Ovary Cancer - Nursing Mx: When is the tumor removed?
If ovarian cancer occurs in young woman and tumor is unilateral.
Ovary Cancer - Nursing Mx: What may be done after childbirth?
Surgical reexploration may be performed, and remaining ovary removed.
Ovary Cancer - Nursing Mx: What is done if both ovaries are involved?
bilateral oophorectomy performed and chemo follows.
Ovary Cancer - Nursing Mx: Pts with advanced ovarian cancer may develop what
ascites and pleural effusion. We would then need to give IV fluids to fix electrolyte imabalcne, administer parenteral nutrition, provide post op care and controlling pain
Ovary Cancer - Nursing Mx: Comfort measurs for women with ascites?
Providing small frequent meals, decreasing fluid intake, administering diuretic agents and providing rest.
Ovary Cancer - Nursing Mx: Those with pleural effusion may expeirnce what?
SOB, hypoxia, pleuritic chest pain and cough. Thoracentesis performed to relieve this.
