[Exam 3] Chapter 23 - -Management of Patients with Chest and Lower Respiratory Tract Disorders Flashcards
Pulmonary Edema: What is this?
The abnormal accumulation of fluid in the lung tissue and alveolar space or sometimes both.
Pulmonary Edema: How is gas exchange here?
Difficult , will be SOB.
Pulmonary Edema: Fluid build up makes it difficult for O2 to do what?
Crossover from alveoli to capillary, gas exchange is impaired
Pulmonary Edema: Cardiogenic is often related to what?
HF, with fluid backing up into the lungs
Pulmonary Edema Non-Cardiogenic: What causes this?
There has been damage to the capillary lining.
Pulmonary Edema Non-Cardiogenic: What can damage to capillary lining be from?
Can be direct injury or indirect injury.
Pulmonary Edema Non-Cardiogenic: Direct injury includes what?
Chest trauma , smoke inhalaiton, pulmonary infection, aspiration, anyhting thats directly injured to capillary lining around alveoli
Pulmonary Edema Non-Cardiogenic: What are some examples of indirect causes?
Sepsis, burns, pancreatitis, something that sets off inflammatory process.
Pulmonary Edema Non-Cardiogenic: What happens to the capillary when injury occurs?
It becomes more permeable, meaning proteins and fluids are going to leak into the intersitial space and push on alveoli.
Pulmonary Edema Non-Cardiogenic: What problems occur when fluid accumulates?
Causes repsiratory difficulties, we arent able to get adequate gas exchange, and see them require a lot of oxygen
Pulmonary Edema Non-Cardiogenic: How is this treated?
You need to manage whatever disease process is causing this issue. If sepsis, treat sepsis. If chest trauma, treat that first.
Pulmonary Edema Non-Cardiogenic: Treatment different between this and Cardiogenic?
They are the same. You are wanting to get fluid out of the lungs except Hypoxia may exist even though we are giving them O2.
Pulmonary Edema Non-Cardiogenic: What does PEEP help with?
Helps open up the collapsed alveoli to help with gas exchange. Sometimes high PEEP doesn’t help them oxygenate. See decreased Sat levels.
Pulmonary Edema Non-Cardiogenic: What usually is activated here to cause this?
Inflammatory process is activated and capillary linings become permeable. Also seen in those with low albumin.
Acute Respiratory Failure: When does this happen?
When the patients cannot ventilate . Aren’t able to do gas exchange and cannot get enough oxygenation.
Acute Respiratory Failure: ABG values for acute?
pH < 7.35
CO2 > 50
PaO2 < 50
Resembles respiratory acidosis
Acute Respiratory Failure: Why does respiratory acidosis occur?
Because ventilaiton is impaired so bad that gas exchange is impaired.
Acute Respiratory Failure: what signs of respiratory acidosis may they show?
May be restless, may be fatigued, may have headache , confused, lethargy.
Can’t get enough oxygenation.
Acute Respiratory Failure: Why may symptoms get worse?
May happen as their respiratory failure gets worse
Acute Respiratory Failure Tx: How can we treat this?
Fix the underlying condition.
If caused by COPD, manage COPD.
May require intubation or ventilation.
Patho of ARDS: What is this?
Severe inflammatory process where there’s alveolar damage that leads to pulmonary edema.
Patho of ARDS: How are their oxygen levels?
Are hypoxic and are unresponsive to increased oxygen levels and PEEP
Patho of ARDS: Mortality rate for those that go into ARDS?
26-58 percent
Patho of ARDS - Causes: THis includes what?
Same causes of non-cardiogenic pulmonary edema.
Pneumonia, Shock, Sepsis, Drug Overdose, Aspiration. Trauma. Acute Injury.
Patho of ARDS - Causes: What occurs immediately after acute lung injury?
Initiation of inflammatory-immune response
Patho of ARDS - Causes: What three changes occur in the inflammatory-immune response?
- Increased capillary membrane permeability
- Decreased Airway Diameter
- Injury to Pulmonary Vasculature
Patho of ARDS - Causes: What happens as capillary membranes have increased permeability?
Alveolar flooding with loss of surfactant leading to alveolar collapse
Patho of ARDS - Causes:What happens when there is a decrease in airway diameter?
Increase in airway resistance and decreased lung compliance leading to increased work of breathing and hypoxemia
Patho of ARDS - Causes:What happens when there is injury to the pulmonary vasculature?
Pulmonary vasoconstriction leading ot decreased cardiac output and alveolar dead space
ARDS - CMs: What will this resemble?
Pulmonary Edema
ARDS - CMs: What are some of the signs seen?
Rapid onset of dyspnea, not responsive to O2, infilrates, fluid showing on X-Ray, and crackles in lungs.
ARDS - CMs: Later on, what does this lead to?
Increased alveolar dead space , meaning alveoli isn’t fuctioning and it’s dead space. Lungs difficult to ventilate.
ARDS - CMs: What will we hear in lungs?
A lot of crackles throughout the lungs,
ARDS - CMs: What sign may we physically see with the patient?
Intercostal retractions, where patient is really struggling to breathe.
ARDS - CMs: How can you differeniate between HF and Lung Issues?
BNP
ARDS - CMs: If BNP is elevated, what does this show
Shows that the left ventricle is stretching and its a heart failure issue.
Mx of ARDS: Mx is similar to what?
Pulmonary Edema, and you have to treat whatever is causing it.
Mx of ARDS: WHy is PEEP useful?
Helps improve oxygenation and increases the fuctional residual capacity and really opens up the alveoli and helping prevent them from collapsing.
Mx of ARDS: How does the increased PEEP pressure in the thoracic cavity affect the heart?
Less room for heart to contract. CO usually decreases a long with blood pressure.
Mx of ARDS: As PEEP goes up, what happens to blood pressure?
May go down.
Mx of ARDS: What is the PaO2 usually kept at?
Above 60 because it is hard to oxygenate them and keep their SAT above 90.
Mx of ARDS - Nutritional Support: How will they receive this?
Through internal feedings.
Mx of ARDS - Pharmacologic Therapy: What treatment may be done?
Patients may be on neuromuscular blocking agents and paralytics just so they can accept the breath from the ventilator. Also sedated.
Mx of ARDS - Pharmacologic Therapy: What other medicatiosn will they be on if not paralyzed?
SEdatives or analgesic to help improve their ventilation.
Mx of ARDS - Pharmacologic Therapy: How does Nitric Oxide help?
Helps improve the VQ ratio, which is the ventilation to perfusion. Helps vasodilate and with oxygenation.
Mx of ARDS - Pharmacologic Therapy: What will they be given since blood pressure may be dropping?
May be put on vasopressors or inotropes or steroids that may help with inflammation
Mx of ARDS - General Supporitve Care: What is one of the most important things to do?
Frequent position changes . Usually prone position (abdomen and chest). because they can breathe better and expand lungs more fully.
Mx of ARDS - General Supporitve Care: Being in the prone position helps the lungs how?
Helps their lungs drain better as well as letting them get a better breath
Mx of ARDS - Ventilator Consideations: What does this mean?
It means patients may be fighting the ventilator and not accepting the breaths that the ventilators are giving them.
Mx of ARDS - Ventilator Consideations: What is a Roto-Prone Bed?
It flips them over and rotates them gently. Improves oxygenation and increases sat levels in ABG quickly.
Ventilation-Perfusion Ratios: What is the V here?
Alveolar Perfusion
Ventilation-Perfusion Ratios: What is the Q here?
Pulmonary Blood Flow
Ventilation-Perfusion Ratios: What is important to consider with ventilaiton and perfusion?
That we are achieving ideal O2 and CO2 exchange.
Ventilation-Perfusion Ratios: What is a VQ ration?
Ventilation-Perfusion Ratio
Ventilation-Perfusion Ratios: What can cause a change in VQ ratio?
When theres hypoxia.
Ventilation-Perfusion Ratios: What is an example of a 1:1 ratio Ventilation-Perfusion Ratios: for VQ ration?
When you have an equal amount of CO2 and O2 entering and exiting the body
Ventilation-Perfusion Ratios: What would occur if there were a shunt present?
Perfusion would exceed ventilation . Blood is going through there but there is a blocokage in alveolus. So no gas exchange occurs.
Ventilation-Perfusion Ratios: What are some examples of no gas exchange occurs because there is a blockage?
Pneumonia, Atelectsis, Mucuous Plug so no gas exchange occurs
Ventilation-Perfusion Ratios: What occurs when there is dead-space within the capillary?
Ventillation exceeds perfusion and the alveoli don’t have adequate blood supply for gas exchange to occur.
Ventilation-Perfusion Ratios: Example of there being more ventillation than perfusion so the body don’t have adequate blood supply?
Pulmonary Embolism , Cardiogenic Shock,
Ventilation-Perfusion Ratios: What is the silent unit?
There is a blockade in the alveoli and also a blockage in the blood flow. Absnece of ventilation perfusion
Ventilation-Perfusion Ratios: What would be some examples of when alveoli and blood flow is blocked
Pneumo, Severe Respiratory Distress
Ventilation-Perfusion Ratios: What is the goal with VQ Ratios?
We want an equal amount of CO2 and O2 to be exchanged.
How does PEEP affect the overall problem of ARDS?
Alveoli is normally closed with with PEEP, it improves:
Oxygenation
Increased Fuctional Residual Capacity
Reverse Alveolar Collapse
Review Questions - ARDS: How does PEEP reverse alveolar collapse?
Prevent collapse and open collapsed
Review Questions - ARDS: Why may systemic hypotension occur in patients with ARDS receiving PEEP?
Systemic hypotension may occur due to hypovolemia secondary to leakage of fluids into the intersitialspaces and depressed cardiac output from high levels of PEEP
Pulmonary Hypertension: What is this?
Increased vascular resistance thats caused by a congenital heart defect, portal hypertension, COPD/PE. Just increased pressure in lungs.
Pulmonary Hypertension CMs: What does this result in?
Dyspnea biggest sign, increased pulmonary artery pressure bc of increased pressure in lungs.
Pulmonary Hypertension Assess/Diagnostic Finding: What Diagnostics could tell us this?
From Increased PA Pressure from right-sided heart cath.
Decreased lung compliance,
Pulmonary Hypertension Medical Mx: How is this treated medication wise?
Smooth muscle relaxers like Viagra or Cilalis.
Pulmonary Hypertension Medical Mx: Paitents with severe pulmonary hypertension may see what issues?
It can cause heart issues and may see a lung transplant done. Even heart transplant as well.
Pulmonary Hypertension Medical Mx: What is the best way to help manage pulmonary hypertension?
Early diagnosing.
Pulmonary Hypertension Medical Mx: Pulmonary Hypertension causes what to hapen to blood vesssels?
Causes them to become constricted
Pulmonary Embolism: What is this?
This is a blockage in the lung artery that originated from venous system form right side of heart so gas exchange will be impaired. Could be absent in the area where blood clot is at.
Pulmonary Embolism: What is the patho of this?
Occurs when blood clots (emboli) become lodged in a lung artery , blocking blood flow to lung tissue
Pulmonary Embolism - RFs: What can cause us to be at risk?
Smoking, HF, Immobility, DVT, Sometimes people are more liekly for this. Afib.
Pulmonary Embolism - CMs: What signs will they have?
They will have dyspnea, chest pain, anxious, tachycardic, hemoptysis (coughing up of blood), they can;t breathe.
Pulmonary Embolism - Assessment/Diagnostics: What may initially be drawn?
D-Dimer, which shows potentially clots being formed.
Pulmonary Embolism - Assessment/Diagnostics: Why may a VQ scan be done?
Looks at ventilation and perfusion.
Pulmonary Embolism - Assessment/Diagnostics: What is most often does?
CTA, which is a chest CT. Looks at vessels within lungs and so it will show if there is a PE present.
Pulmonary Embolism - Assessment/Diagnostics: What is the last diagnostic that may be done?
Pulmonary Angiography, which is similar to heart cath. Catheter threaded up to see if there is a blockage within the lung.
Pulmonary Embolism - Prevention: What can be done to prevent this for hospital pts.
Patients can wear SCDs in hospital.
Lovenox injection
Anticoagulants. Reduce venous stasis.
Mx of PE - Pharmacologic Therapy: What must we do if someone is coming in with a present PE?
It is considered an emergency. We need to make sure patient is put on O2, NC, and IV is stated. Start EKG and draw labs and do CTA or VQ scan and manage anxieety.