EXAM 3 START: Panopto 25 Integument Flashcards
How much of the body mass does skin make up?
15-20%
What are the 5 functions of skin?
- Sensory: Detailed, specific info about our external environment through receptors
- Homeostasis: regulates body temperature, radiates heat and sweat, and lowers body temperature.
- Protection: defense function, barrier function, participation in the immune response and antigen processing
- Excretion: Glands embedded in the skin, getting rid of excess electrolytes through sweat
- Other: calcium metabolized, forming vitamin D3, attracting the sexes: some glands excrete both signaling molecules that the opposite sex notices
What are the 2 main layers of the skin?
Epidermis and Dermis
what is the outside layer of skin or the layer we can see?
epidermis
What kind of epithelium is the epidermis made of?
keratinized stratified squamous epithelium
is the dermis the outer layer or the inner layer?
inner layer underneath the epidermis
which is thicker the dermis or epidermis?
dermis
what does the dermis consist of
connective tissue
what are some things the dermis includes?
hair follicles, blood vessels, smooth muscle
what are the 2 layers of the dermis?
- Papilary layer
- Reticular layer
describe the papilary layer
papilae, loose connective tissue layer with elastic fibers and collagen that are randomly woven (no pattern), thin layer
describe the reticular layer
thicker layer, dense connective tissue, larger bundles of fibers: collagen and elastic fibers; collagen is in long parallel lines (langer lines).
which layer is important for a surgeon to understand?
the reticular layer of the dermis. they need to cut between the fibers not across to avoid scaring
hypodermis
underneath the dermis, largely white fat, subcutaneous fat. For energy storage
what is another term for the hypodermis?
subcutaneous layer
Is the hypodermis part of the skin?
no it is below the dermis
Is the epidermis simple or stratified
stratified, it has 5 layers
List the layers of the epidermis from the bottom layer to the uppermost outer layer
- stratum Basale
- stratum spinosum
- stratum granulosum
- stratum lucidum
- stratum corneum
what is another term for stratum basale?
stratum germinatevum
what kind of epithelium does the stratum basale have?
anything but squamous, vary between cuboidal and columnar
is the stratum basale simple or stratified
simple one layer
what happens in the stratum basale?
cell division its a germ layer
describe the stratum spinosum
prickly appearance, look like spines, finger like projections of the cell surface that adhere to the projections of the adjacent cell.
what is the point of adhesion between projections in the stratum spinosum called?
desmosomes
Where do desmosomes in the stratum spinosum reside?
in the intercellular space
Can we see desmosomes in the light microscope?
no unless they are in the skin because they are in groups
node of bizzero
in the stratum spinosum, groups of desmosomes
Malpighian layer
first 2 layers of the epidermis, stratum basale and stratum spinosum
How many cells thick is the stratum granulosum?
2-4 cells thick, and the cells are flattened and keratinized
what causes cells in the stratum granulosum to be granular?
flattened cells and keratin
what are the basophilic granules made of in the stratum granulosum ?
keratohyaline
what happens to the number of granules in the stratum granulosum when you go from the first cell to the top layer?
there is a gradual increase in both number and size of these granules (first step in the formation of keratin)
what comes together to make keratin in the stratum granulosum
Keratohyaline + cytokeratin -> keratin
what is the intermediate filament protein called?
keratin
what is the intermediate filament called?
tonofilament
are the stratum lucidum or stratum granulosum cells flatter?
lucidum
what color are the cells in the stratum lucidum?
clear and transparent
are there granules in the stratum lucidum?
no
are cells in the stratum lucidum basophilic or acidophilic
acidophilic
What are cells filled with in the stratum lucidum that make them acidophilic?
eleidin
what is eleidin considered in the formation of keratin
intermediate
what areas of the skin have the stratum spinosum?
thick skin: only in the feet and palms of hands
are thin and thick considered skin
no because to be skin you must have a dermis and epidermis
is the thick skin at the base of our neck considered thick skin or thin skin?
thin skin because its not the palms of our hands feet
where do we find thin skin?
everywhere but the palms of the hands and feet
stratum corneum
outermost layer/surface layer, by the time the cells get here they are dead, and now we have keratin. this layer varies greatly in thickness
callus
In areas with friction, skin is the thickest so it provides a barrier