Exam 3 - OA, Gout Meds

Question 1

OTC NSAIDS

Answer 1

Ibuprofen
Naprosyn
ASA

Question 2

Rx NSAIDS

Answer 2

Celecoxib (Celebrex)
Diclofenac
Fenoprofen
Indomethacin
Ketolorlac

Question 3

NSAID GI side effects

Answer 3

stomach pain
ulcer
constipation/diarrhea
MI, stroke
rebound HA

Question 4

is ASA a common treatment for OA

Answer 4

not any longer

Question 5

colchicine has what type of effect

Answer 5

anti-inflammatory but is not a “pain medicine”

Question 6

colchicine is use for __ __ gout treatment

Answer 6

acute attack

Question 7

what does probenecid (Probalan) do?

Answer 7

inhibits renal reabsorption of urates, increases urinary excretion of uric acid

Question 8

should you take ASA and probenecid together?

Answer 8

No, it will become inactivated

Question 9

Can you take probenecid with alcohol?

Answer 9

No

Question 10

How much water should you drink with probenecid and why?

Answer 10

at least 2L/daily

can lead to renal failure, monitor renal function

Question 11

is probenecid as effective when Crt clearance is decreased

Answer 11

No

Question 12

first line drug, most common Rx for gout maintenance

Answer 12

Allopurinol (Zyloprim)

Question 13

how does Allopurinol work?

Answer 13

acts to decrease production of uric acid

Question 14

Allopurinol side effects

Answer 14

HA
dizziness
**on PPT

N/V/D
abdominal pain
bone marrow depression

Question 15

common labs for pt taking OA and gout meds

Answer 15

liver function test
kidney function test
–BUN, Crt clearance
Uric acid levels

Question 16

Losartan (Cozaar) effects for gout

Answer 16

promotes uric acid excretion

*monitor BP

Question 17

probenecid (Probalan) side effects

Answer 17

nausea

rash

Question 18

when to avoid taking or increasing dose of Allopurinol?

Answer 18

if an active flare is present