Exam 3 inflammatory blistering diseases Flashcards

1
Q

What are the hallmarks of HSV-1?

A

Above neck, mouth lesions, less recurrence than HSV-2

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2
Q

What are the hallmarks of HSV-2

A

genitalia STD, recurrent

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3
Q

What are the hallmarks of vericella (chicken pox)?

A

dew drops of a rose petal (chicken pox)

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4
Q

What are the hallmarks of herpes zoster?

A

Unilateral dermatome has many lesions

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5
Q

What are the hallmarks of impetigo?

A

honey-colored crusting

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6
Q

What are the hallmarks of bullous pemphigoid?

A

Tense blisters (don’t move much)

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7
Q

What is the disease associated with dermatitis herpetiformus?

A

celiac’s disease, gets worse with gluten

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8
Q

What is the hallmark of pemphigus vulgaris

A

flaccid blisters

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9
Q

What is the hallmark of porphyria cutanea tarda

A

hyperpigmentation

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10
Q

What do infections of HSV-1 and HSV-2 occur?

A

HSV-1 is in childhood, HSV2 is STD of adults

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11
Q

What is a specific treatment of HSV1

A

acycolvir (oral), famciclovir, valacyclovir, contagion prevention

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12
Q

How long does the varicella virus take to incubate?

A

14 days

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13
Q

What are the prodromes of varicella?

A

fever, chills, malaise, 2-3 days before onset of rash

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14
Q

What are major complications of varicella?

A

encephalitis, pneumonia, hepatitis, Reye’s syndrome, can become septic with secondary infections

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15
Q

What is the immunization schedule for varicella?

A

2 doses: 1st at 12-15 months then 2nd at 4-6 years. People over 13 years should get 2 doses 28 days apart

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16
Q

What is the prodrome of herpes zoster?

A

pain along nerve root up to 5 days prior to rash

17
Q

What else should you rule out with herpes zoster?

A

Immunosuppression (cancer, HIV, connective tissue disease

18
Q

What are the current treatments of herpes zoster?

A

acyclovir (PO, IV), prednisone

19
Q

What should you worry about with a herpes zoster outbreak on the face?

A

Infection of the eye leading to blindness

20
Q

How quickly should you treat herpes zoster to reduce post-herpetic neuralgia?

A

Treat within 48 hours

21
Q

What causes non-bullous impetigo?

A

Group A strep pyogenese (catalase-, Beta hemolytic) staph aureus (catalase+, coagulase+), mixed infection

22
Q

What causes bullous impetigo?

A

group II staph aureus (contains epidermolytic toxin)

23
Q

What’s more common, bullous or non-bullous impetigo?

A

non-bullous

24
Q

What is non-bullous impetigo?

A

single red macule or papule that becomes vesicle that erups and forms an erosion that dries to make honey-colored crust

25
What is bullous impetigo?
Superficial vesicles that progress rapidly to flaccid bullae with sharp margins and no surrounding erythema, eruption leads to yellow crust with oozing
26
Should you pop impetigo pustules?
NO
27
Treatment of bullous impetigo?
Hygienic measures, topical antibiotics, oral antibiotics
28
Name the different bullous diseases (all autoimmune)
Bullous pemphigoid, pemphigus vulgaris, dermatitis herpetiformis
29
Describe bullous pemphigoid. treatment?
Tensile bullae on normal or erythematous skin; prednisone, topical cortisone
30
Describe dermatitis herpetiformis. What disease is it associated with?
autoimmune condition with clusters of erythematous papules, pruritic and distributed symmetrically along extensor surfaces; Associated with Celiac's
31
Describe pemphigus vulgaris
flaccid blisters on head, trunk and intertriginous areas, Nikoslky sign
32
What condition results in porphyria cutanea tarda?
deficiency in heme-synthesizing enzyme
33
Describe porphyria cutanea tarda?
blistering of skin in sun-exposed areas, hyperpigmentation
34
What are risk factors for porphyria cutanea tarda?
hepatitis C, hemochromatosis and alcoholism