Exam 3 inflammatory blistering diseases

Question 1

What are the hallmarks of HSV-1?

Answer 1

Above neck, mouth lesions, less recurrence than HSV-2

Question 2

What are the hallmarks of HSV-2

Answer 2

genitalia STD, recurrent

Question 3

What are the hallmarks of vericella (chicken pox)?

Answer 3

dew drops of a rose petal (chicken pox)

Question 4

What are the hallmarks of herpes zoster?

Answer 4

Unilateral dermatome has many lesions

Question 5

What are the hallmarks of impetigo?

Answer 5

honey-colored crusting

Question 6

What are the hallmarks of bullous pemphigoid?

Answer 6

Tense blisters (don’t move much)

Question 7

What is the disease associated with dermatitis herpetiformus?

Answer 7

celiac’s disease, gets worse with gluten

Question 8

What is the hallmark of pemphigus vulgaris

Answer 8

flaccid blisters

Question 9

What is the hallmark of porphyria cutanea tarda

Answer 9

hyperpigmentation

Question 10

What do infections of HSV-1 and HSV-2 occur?

Answer 10

HSV-1 is in childhood, HSV2 is STD of adults

Question 11

What is a specific treatment of HSV1

Answer 11

acycolvir (oral), famciclovir, valacyclovir, contagion prevention

Question 12

How long does the varicella virus take to incubate?

Answer 12

14 days

Question 13

What are the prodromes of varicella?

Answer 13

fever, chills, malaise, 2-3 days before onset of rash

Question 14

What are major complications of varicella?

Answer 14

encephalitis, pneumonia, hepatitis, Reye’s syndrome, can become septic with secondary infections

Question 15

What is the immunization schedule for varicella?

Answer 15

2 doses: 1st at 12-15 months then 2nd at 4-6 years. People over 13 years should get 2 doses 28 days apart

Question 16

What is the prodrome of herpes zoster?

Answer 16

pain along nerve root up to 5 days prior to rash

Question 17

What else should you rule out with herpes zoster?

Answer 17

Immunosuppression (cancer, HIV, connective tissue disease

Question 18

What are the current treatments of herpes zoster?

Answer 18

acyclovir (PO, IV), prednisone

Question 19

What should you worry about with a herpes zoster outbreak on the face?

Answer 19

Infection of the eye leading to blindness

Question 20

How quickly should you treat herpes zoster to reduce post-herpetic neuralgia?

Answer 20

Treat within 48 hours

Question 21

What causes non-bullous impetigo?

Answer 21

Group A strep pyogenese (catalase-, Beta hemolytic) staph aureus (catalase+, coagulase+), mixed infection

Question 22

What causes bullous impetigo?

Answer 22

group II staph aureus (contains epidermolytic toxin)

Question 23

What’s more common, bullous or non-bullous impetigo?

Answer 23

non-bullous

Question 24

What is non-bullous impetigo?

Answer 24

single red macule or papule that becomes vesicle that erups and forms an erosion that dries to make honey-colored crust

Question 25

What is bullous impetigo?

Answer 25

Superficial vesicles that progress rapidly to flaccid bullae with sharp margins and no surrounding erythema, eruption leads to yellow crust with oozing

Question 26

Should you pop impetigo pustules?

Answer 26

NO

Question 27

Treatment of bullous impetigo?

Answer 27

Hygienic measures, topical antibiotics, oral antibiotics

Question 28

Name the different bullous diseases (all autoimmune)

Answer 28

Bullous pemphigoid, pemphigus vulgaris, dermatitis herpetiformis

Question 29

Describe bullous pemphigoid. treatment?

Answer 29

Tensile bullae on normal or erythematous skin; prednisone, topical cortisone

Question 30

Describe dermatitis herpetiformis. What disease is it associated with?

Answer 30

autoimmune condition with clusters of erythematous papules, pruritic and distributed symmetrically along extensor surfaces; Associated with Celiac’s

Question 31

Describe pemphigus vulgaris

Answer 31

flaccid blisters on head, trunk and intertriginous areas, Nikoslky sign

Question 32

What condition results in porphyria cutanea tarda?

Answer 32

deficiency in heme-synthesizing enzyme

Question 33

Describe porphyria cutanea tarda?

Answer 33

blistering of skin in sun-exposed areas, hyperpigmentation

Question 34

What are risk factors for porphyria cutanea tarda?

Answer 34

hepatitis C, hemochromatosis and alcoholism