Exam 3: Cell-cell interactions (Class 1) Flashcards
What is an emergent property?
A property that a collection/complex system has, but the individual members do not have
What is epithelial tissue?
A sheet of cells that covers a body surface or lines a body cavity
In order for multicellularity to occur…
cells have to be bound together
Sequence of connections in the epithelium
Epithelial tissue –> basal lamina –> connective tissue
What bears the stresses of tension and compression
The extracellular matrix
What transmits stresses from cell to cell
Cytoskeletal filaments anchored to cell-matrix and cell-cell adhesion sites
What is the condition where mutations in proteins cause epithelia to not adhere to the basal lamina?
Epidermolysis Bullosa
3 types of cell-cell attachments
- tight junctions
- desmosomes
- gap junctions
Function of tight junctions
seal cells together
Function of desmosomes
connect the cytoskeletons of cells
Function of gap junctions
act as channels between cells
What are tight junctions composed of
Specialized proteins
Where are tight junctions located
In the plasma membranes of adjacent animal cells
How do the proteins in tight junctions orient themselves?
They line up and bind to each other
Where do the proteins in tight junctions bind?
Between the two plasma membranes
What does the stitching of the two cells in tight junctions form?
A watertight seal
Which types of tissues are desmosomes common in?
Epithelial and muscle
What do the proteins of desmosomes bind to? (2 answers)
- to each other
- to proteins that anchor intermediate filaments