Exam 2: Glycolysis Flashcards
Step 1: What happens?
Phosphate group is added to glucose, forming G6P
Step 1: What facilitates?
Hexokinase
Step 2: What happens?
G6P becomes a 5-member ring, forming F6P
Step 2: What facilitates?
PGI (phosphoglucose isomerase)
Step 3: What happens?
Phosphate is added to F6P, forming F-1,6BP
Step 3: What facilitates?
PFK (phosphofructokinase)
Step 4: What happens?
F-1,6BP is cleaved, forming DAP and G3P
Step 4: What facilitates?
Aldolase
Step 5: What happens?
DAP re-arranges to form G3P, now there are 2 G3P molecules
Step 5: What facilitates?
triose isomerase phosphate
Step 6: What happens?
Phosphate is added to G3P forming 1,3-BPG, NAD+ is reduced to NADH
Step 6: What facilitates?
GAPDH (glyceraldehyde-3-phosphate-dehydrogenase), paired with step 7
Step 7: What happens?
Phosphate removed from 1,3-BPG to form 3PG, and ATP
Step 7: What facilitates?
PGK (phosphoglycerate kinase), paired with step 7
Step 8: What happens?
3PG is re-arranged to 2PG