EXAM 3- Antibacterial Drugs interfere with DNA/RNA

Question 1

fluorquinolones

Answer 1

interfere with a DNA enzyme needed for synthesis of DNA

Question 2

miscellanous anti-infectives:

Answer 2

• inhibit RNA/DNA synthesis

- Inhibit cell wall synthesis

Question 3

examples of fluorquinolones

Answer 3

-ciprofloxacin (Cipro)
-levofloxacin (Levaquin)
-ofloxacin
(xacin’s)

Question 4

examples of miscellanous anti-infectives

Answer 4

• metronidazole (Flagyl)

- rifaximin (Xifaxan)

Question 5

uses of fluorquinolones

Answer 5

-gram-positive and negative bacteria

Lower respiratory infections, bone/joint infections, UTI’s, skin infections, and STI’s

Question 6

uses of miscellanous anti-infectives

Answer 6

-VRE, Serious infections such as C. diff, endocarditis, septicemia

Question 7

adverse reactions of fluorquinolones

Answer 7

• Nausea
• Diarrhea
• Headache
• Abdominal pain or discomfort
• Dizziness
• Photosensitivity

Question 8

adverse reactions of miscellanous anti-infectives

Answer 8

• Nausea
• Vomiting
• Rash
• Insomia
• Nephrotoxicity
• Ototoxicity
• Chills
• Fever

Question 9

nursing process

Answer 9

• Identify signs/symptoms of the infection
• Evaluate IM sites for soreness
• Evaluate IV sites for inflammation or extravasation
• Evaluate for superinfections
• Evaluate for s/s of serious reactions
• Oto-nephro-neurotoxicty

Question 10

monitor blood levels

Answer 10

peak, trough, monitor CBC

Question 11

Peak

Answer 11

time of maximum effect, commonly measured immediately after the drug has been infused

Question 12

trough

Answer 12

level before the next dose (30 minutes before dose)

Question 13

monitor CBC

Answer 13

especially WBC and differential to eval effectiveness (WBC will decrease to normal range)