Exam 2 - Lecture 31 (Female Repro. System) Flashcards
What are the 4 steps to ovary development?
- Cells from degenerating mesonephric tubule move into the ovary
- Germ cells end up in gonadal cords (oocytes)
- Oocytes break away from cords and isolate
- Each oocyte is surrounded by follicular cells
Where do follicular cells come from?
Degeneration of mesonephric tubules
What 5 things does the paramesonephric duct give rise to?
- Uterine tube
- Uterine horn
- Uterine body
- Cervix
- Part of vagina
What 2 things does the urogenital sinus give rise to in females?
- Vestibule
2. Part of vagina
What is uterus didelphys and what animals have it?
2 cervices, 2 vaginas, 2 uteri
Marsupials
What is vagina simplex/uterus duplex and what animals have it?
2 uteri, 2 cervical canals, 1 vagina
Rabbits/rodents
What is uterus bicornis and what animals have it?
2 uterine horns, 1 uterine body, 1 cervix, 1 vagina
domestic mammals
What animal has the largest uterine body?
horse
What is unique to the uteri of primates?
They have a body and uterine tubes but no uterine horns
What are the 3 parts of the embryonic external genitalia at the indifferent stage?
- Genital tubercle
- Urogenital folds
- Labioscrotal swellings
What does the genital tubercle differentiate into in the male?
Penis (glans, corpus cavernosum, corpus spongiosum)
What does the genital tubercle differentiate into in the female?
Clitoris (glans, corpus cavernosum, bulb of vestibule)
What do the urogenital folds differentiate into in the male?
Ventral aspect of penis
What do the urogenital folds differentiate into in the female?
labia of the vulva
What do the labioscrotal swellings differentiate into in the male?
scrotum
What do the labioscrotal swellings differentiate into in the female?
Doesn’t/poorly develops
Primates = labia majora
What is the default gender is testosterone is absent?
Female
What are the 3 steps in development of external female genitalia?
- Anus separates from cloacal fold
- Urogenital fold –> vulvular lips
- Genital tubercle –> clitoris
What are the 3 steps in development of external male genitalia?
- Anus separates from cloacal fold
- Genital tubercle begins to form glans and labioscrotal swellings develop on either side
- Urogenital fold gets smaller and eventually closes
- Genital tubercle –> glans of penis
What is anogenital distance?
Distance between anus and whatever structure the genital tubercle becomes (glans penis/clitoris)
What are the 5 malformations of genitalia?
- Genital hypoplasia
- Cryptorchidism
- Stenosis of the ducts, abnormal fusion
- Hypospadia
- Intersex conditions