Exam 2 - Lecture 26 (Intro to Embryology) Flashcards

1
Q

What are congenital defects?

A

Defects that are present at birth (may not know about it right away or ever)

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2
Q

What are two types of congenital defects?

A
  1. Genetic

2. Environmental (drugs, plants, infections, pesticides, radiation, etc.)

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3
Q

What environmental factor plays a big role in veterinary congenital defects?

A

Drugs (vax, orals, topicals, etc.)

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4
Q

What environmental factor plays a big role in congenital defects in herbivores?

A

Plants

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5
Q

What is multifactorial inheritance?

A

A couple of different factors come together to cause birth defects

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6
Q

What are birth defects usually a combo of?

A

Genetic and environmental causes

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7
Q

What is the highest % of causes of birth defects in vet med?

A

Unknown

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8
Q

What is a critical period?

A

Point in time when an organ/organ system is developing, cells are undergoing replication, fetus is MOST exposed to outside influences

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9
Q

What are the two things that are a part of the first critical period of development in the cat?

A

brain and spinal cord

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10
Q

What critical period extends into postnatal time in the cat?

A

Development of cerebellum and cerebrum

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11
Q

What happens if an ewe eats Veratrum californicum at day 14-15 of gestation?

A

Cycloptic/monkey-faced lamb

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12
Q

What plant results in a cycloptic/monkey-faced lamb if the ewe ingests it/what day of gestation?

A

Veratrum californicum @ day 14-15

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13
Q

What is cerebellar hypoplasia?

A

Small or underdeveloped cerebellum

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14
Q

What are the 3 general causes for cerebellar hypoplasia?

A

genetic, infectious, and toxic

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15
Q

What are 2 infectious causes for cerebellar hypoplasia?

A
  1. Bovine Viral Diarrhea (BVD)

2. Feline panleukopenia

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16
Q

When is the calf affected in BVD?

A

100-170 days of gestation

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17
Q

When is the kitten affected in feline panleukopenia?

A

Last part of gestation (9-14d) to early postnatal period (9-14d postnatally) (has to be infected during critical period)

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18
Q

What can totipotent cells give rise to?

A

Entire, complete organism

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19
Q

As stem cells differentiate, there is increased _____ on what the cell can become.

A

Restriction

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20
Q

What is the zona pellucida?

A

Outer layer surrounding the ovum during the first cell cleavage division

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21
Q

What are blastomeres?

A

Early daughter cells that divide

22
Q

How many blastomeres are present in the second cleavage division?

A

4

23
Q

What is a morula?

A

Mulberry shaped phase of cell cleavage that consists of outer and inner blastomeres.

24
Q

What is a blastula and what are its components?

A

Phase of cell cleavage where the outer layer is trophoblasts, inner blastomeres are present just inside the trophoblasts, and the cavity is the blastocoele.

25
Q

What is the role of the blastocoele?

A

To aid in diffusion

26
Q

When the zona pellucida is in place, the cell number _____ but their size _____.

A

increases; decreases

27
Q

What is the fate of outer blastomeres in the morula?

A

Form placenta/trophoblasts

28
Q

What is the fate of inner blastomeres in the morula?

A

They are not restricted; contribute to inner cell mass (embryo) of the blastula

29
Q

What does gastrulation give rise to?

A

The 3 germ layers

30
Q

Gastrulation marks the beginning of _____.

A

Organ and body development

31
Q

When does gatrulation occur?

A

14d into gestation

32
Q

What are the 2 cavities of the developing embryo?

A
  1. Embryonic cavity

2. Yolk sac

33
Q

The embryo is a _____ disc.

A

bilaminar

34
Q

What are the two layers of the bilaminar disc?

A

Epiblast cells (tall) and hypoblast cells (shorter, underneath epi)

35
Q

What 2 things form at the beginning of gastrulation and where?

A
  1. Primitive streak
  2. Primitive node
    Form in the amniotic cavity
36
Q

What 4 things can you tell from the primitive streak and node?

A

R/L, Cranial/Caudal (head/tail)

37
Q

Epiblast cells flow through the _____ to give rise to the 3 germ layers.

A

primitive groove

38
Q

Epiblast cells that flow deep through the primitive groove give rise to _____.

A

Endoderm

39
Q

Epiblast cells that flow through the primitive groove to an intermediate location give rise to _____.

A

Mesoderm

40
Q

Epiblast cells that don’t migrate through the primitive groove give rise to _____.

A

Ectoderm

41
Q

At the notochord, epiblast cells flow through the _____.

A

primitive node

42
Q

Epiblast cells that flow through the primitive node flow in a _____ direction and lie between _____ and _____.

A

cranial; ectoderm; endoderm

43
Q

What 3 things does ectoderm give rise to?

A
  1. Epidermis
  2. Neural tissue
  3. Skeletal/c.t. of the head
44
Q

What 2 things does endoderm give rise to?

A
  1. Lining of the digestive and respiratory tracts

2. Organs of digestion

45
Q

What 4 things does mesoderm give rise to?

A
  1. Muscle
  2. Skeletal tissue
  3. Urogenital
  4. Cardiovascular
46
Q

What develops within the mesoderm to kick off the start of body formation/coelom closure?

A

tiny cavities/coelomic vesicles

47
Q

What do the coelomic vesicles form when they combine?

A

coelom

48
Q

What 2 things form along with the formation of the coelom?

A

Splanchnic and somatic mesoderm

49
Q

What does splanchnic mesoderm eventually give rise to?

A

internal organs

50
Q

What does somatic mesoderm eventually give rise to?

A

body wall

51
Q

Which way do splanchnic and somatic mesoderms grow and what do they form?

A

ventrally and medially; form gut tube and closure of embryo

52
Q

What is schistosomus reflexus and what happens as a result?

A

Condition where somatic mesoderm never made contact ventrally; head and legs are at one end of the body while viscera is at the other end.