Exam 2 - Lecture 26 (Intro to Embryology) Flashcards
What are congenital defects?
Defects that are present at birth (may not know about it right away or ever)
What are two types of congenital defects?
- Genetic
2. Environmental (drugs, plants, infections, pesticides, radiation, etc.)
What environmental factor plays a big role in veterinary congenital defects?
Drugs (vax, orals, topicals, etc.)
What environmental factor plays a big role in congenital defects in herbivores?
Plants
What is multifactorial inheritance?
A couple of different factors come together to cause birth defects
What are birth defects usually a combo of?
Genetic and environmental causes
What is the highest % of causes of birth defects in vet med?
Unknown
What is a critical period?
Point in time when an organ/organ system is developing, cells are undergoing replication, fetus is MOST exposed to outside influences
What are the two things that are a part of the first critical period of development in the cat?
brain and spinal cord
What critical period extends into postnatal time in the cat?
Development of cerebellum and cerebrum
What happens if an ewe eats Veratrum californicum at day 14-15 of gestation?
Cycloptic/monkey-faced lamb
What plant results in a cycloptic/monkey-faced lamb if the ewe ingests it/what day of gestation?
Veratrum californicum @ day 14-15
What is cerebellar hypoplasia?
Small or underdeveloped cerebellum
What are the 3 general causes for cerebellar hypoplasia?
genetic, infectious, and toxic
What are 2 infectious causes for cerebellar hypoplasia?
- Bovine Viral Diarrhea (BVD)
2. Feline panleukopenia
When is the calf affected in BVD?
100-170 days of gestation
When is the kitten affected in feline panleukopenia?
Last part of gestation (9-14d) to early postnatal period (9-14d postnatally) (has to be infected during critical period)
What can totipotent cells give rise to?
Entire, complete organism
As stem cells differentiate, there is increased _____ on what the cell can become.
Restriction
What is the zona pellucida?
Outer layer surrounding the ovum during the first cell cleavage division