exam 2 class 10 Flashcards
what is the equation for hemoglobin?
Hb + O2 ->HbO2
1 hemoglobin molecule can bind to how many oxygen molecules?
4
Hemoglobin bound to oxygen
oxyhemoglobin (HbO2)
Amount of oxygen bound to hemoglobin at any given is expressed as?
% saturation of Hb
If all binding sites on all hemoglobin molecules are occupied by oxygen
molecules then what?
the blood is 100% oxygenated, or saturated with oxygen
If half the available binding sites are carrying oxygen?
the hemoglobin is 50%
saturated, and so on
relationship between
and how much oxygen binds to hemoglobin in vitro
Oxyhemoglobin saturation curves
At normal alveolar and arterial (100 mm
Hg) how much hemoglobin is bound to O2?
98% of the hemoglobin is bound to O2
Above 60 mm Hg, hemoglobin is more than 90% saturated?
to maintain near-normal
levels of oxygen transport
having a higher
oxygen affinity than adult hemoglobin (HbA)
Fetal hemoglobin (HbF)
how long does it take for babies to automatically switch from producing
HbF to producing HbA?
2 years for the switch to be complete
Shift in Hb saturation curve that results from a change
in pH is called the?
Bohr effect
At a of 40 mm Hg (equivalent to a resting cell) and pH of 7.4, hemoglobin is about _______ saturated
75%
At the same if the pH falls to 7.2, the percent
saturation decreases to about 62%. Hb releases
______ more oxygen at pH 7.2 than they do at pH
7.4
13%
When does body undergo shifts in blood pH?
during exercise
Increasing temperature decreases ?
the affinity of Hb for O2
Carbon dioxide increases ____________________ and lowers ______________
-hydrogen ion concentration
-tissue pH
more CO2 in blood
lower pH
what is the inner lining of blood vessels made of?
thin layer of endothelium