exam 2 class 10 Flashcards

1
Q

what is the equation for hemoglobin?

A

Hb + O2 ->HbO2

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2
Q

1 hemoglobin molecule can bind to how many oxygen molecules?

A

4

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3
Q

Hemoglobin bound to oxygen

A

oxyhemoglobin (HbO2)

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4
Q

Amount of oxygen bound to hemoglobin at any given is expressed as?

A

% saturation of Hb

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5
Q

If all binding sites on all hemoglobin molecules are occupied by oxygen
molecules then what?

A

the blood is 100% oxygenated, or saturated with oxygen

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6
Q

If half the available binding sites are carrying oxygen?

A

the hemoglobin is 50%
saturated, and so on

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7
Q

relationship between
and how much oxygen binds to hemoglobin in vitro

A

Oxyhemoglobin saturation curves

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8
Q

At normal alveolar and arterial (100 mm
Hg) how much hemoglobin is bound to O2?

A

98% of the hemoglobin is bound to O2

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9
Q

Above 60 mm Hg, hemoglobin is more than 90% saturated?

A

to maintain near-normal
levels of oxygen transport

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10
Q

having a higher
oxygen affinity than adult hemoglobin (HbA)

A

Fetal hemoglobin (HbF)

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11
Q

how long does it take for babies to automatically switch from producing
HbF to producing HbA?

A

2 years for the switch to be complete

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12
Q

Shift in Hb saturation curve that results from a change
in pH is called the?

A

Bohr effect

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13
Q

At a of 40 mm Hg (equivalent to a resting cell) and pH of 7.4, hemoglobin is about _______ saturated

A

75%

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14
Q

At the same if the pH falls to 7.2, the percent
saturation decreases to about 62%. Hb releases
______ more oxygen at pH 7.2 than they do at pH
7.4

A

13%

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15
Q

When does body undergo shifts in blood pH?

A

during exercise

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16
Q

Increasing temperature decreases ?

A

the affinity of Hb for O2

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17
Q

Carbon dioxide increases ____________________ and lowers ______________

A

-hydrogen ion concentration
-tissue pH

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18
Q

more CO2 in blood

A

lower pH

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19
Q

what is the inner lining of blood vessels made of?

A

thin layer of endothelium

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20
Q

walls of blood vessels are composed of?

A

(1) smooth muscle
(2) elastic connective tissue
(3) fibrous connective tissue

21
Q

narrows the diameter
of the vessel lumen

A

vasoconstriction

22
Q

widens the diameter
of the vessel lumen

A

vasodilation

23
Q

arterioles, capillaries, small post capillary vessels (venules) are all called?

A

microcirculation

24
Q

have a lining that contains pores that let only small molecules pass through. Nervous system, skin and lungs

A

Continuous capillaries

25
Q

have larger openings between the cells that allow the quick exchange of substances. Kidneys,
small intestine and endocrine glands

A

Fenestrated capillaries

26
Q

discontinuous, have even larger gaps and pores. Liver, spleen, lymph nodes, bone marrow and endocrine glands

A

Sinusoidal capillaries

27
Q

what in the veins prevent backflow of blood

A

valves

28
Q

When the skeletal muscles compress the veins, they force blood toward?

A

the heart (skeletal muscle pump)

29
Q

contraction of the ventricles pushes blood into the elastic arteries causing them to stretch

A

ventricular contraction

30
Q

elastic recoil in the arteries maintains driving pressure during ventricular diastole

A

ventricular relaxation

31
Q

where is blood pressure the highest?

A

in the arteries

32
Q

blood pressure decreases when?

A

blood flows through the circulatory system

33
Q

Highest pressure in the
circulatory system created by the contraction of ventricles of heart

A

Systolic Pressure (SP)

34
Q

Lowest pressure in the
circulatory system associated with the
relaxation of ventricles of heart

A

Diastolic Pressure (DP)

35
Q

Abnormally high or low arterial blood pressure can be indicative of?

A

a problem in the cardiovascular system

36
Q

blood pressure falls too low

A

hypotension

37
Q

blood flow and oxygen
supply to the brain are impaired, and the person may become dizzy or
faint

A

hypotension

38
Q

blood pressure is chronically elevated

A

hypertension

39
Q

high pressure
on the walls of blood vessels may cause weakened areas to rupture and bleed into the tissues

A

hypertensive

40
Q

rupture occurs in the brain

A

cerebral hemorrhage

41
Q

cerebral hemorrhage and may cause

A

a stroke

42
Q

rapid pressure increase that occurs when the left ventricle pushes
blood into the aorta can be felt as a

A

pulse or pressure wave

43
Q

measure of the strength of the pressure wave,
is defined as systolic pressure minus diastolic pressure

A

pulse pressure PP

44
Q

PP=?

A

SP-DP

45
Q

Arterial pressure is pulsatile, so we use a single value

A

the mean arterial pressure (MAP)

46
Q

MAP =?

A

DP + 1/3 (SP- DP)

47
Q

Distribution of systemic blood varies according to?

A

the metabolic needs
of individual organs and is governed by a combination of local control
mechanisms and homeostatic reflexes

48
Q

distribution of blood to tissues is represented as

A

(1) % of total flow
(2) Volume per 100 g of tissue per min
(3) Absolute rate of flow (L/min)