exam 1 class 8 Flashcards

1
Q

does gas exchange in the lungs move down or up conc. gradient?

A

down

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2
Q

what happens when arterial blood reaches the tissue capillaries

A

gradient is reserved

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3
Q

what is the main factor that affects atmospheric oxygen content

A

altitude

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4
Q

does partial pressure increase or decrease s you go from sea level to higher altitudes

A

decreases

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5
Q

low alveolar ventilation

A

hypoventilation

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6
Q

lower than normal values of fresh air in the alveoli and less blood oxygen level

A

hypoxia

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7
Q

factors affecting alveolar gas exchange
1. oxygen reaching the lungs ->

A

composition of inhaled air

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8
Q

factors affecting alveolar gas exchange
2. alveolar ventilation ->

A
  • airway resistance
  • ability of lung to stretch
  • rate and depth of breathing
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9
Q

CNS depression does what ?

A

slows ventilation rate and decreases depth of breathing

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10
Q

causes of CNS
depression

A

alcohol poisoning and
drug overdoses

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11
Q

The transfer of oxygen from alveoli to blood requires diffusion across the barrier created by__________________

A

type I alveolar cells and the capillary endothelium

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12
Q

factors affecting aveolar gas diffusion
3. gas diffusion between air and blood

A
  • surface area
  • diffusion distance
  • barrier permeability
  • concentration gradient
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13
Q

factors that make alveolar gas exchange much harder?

A
  1. decrease in amount of alveolar SA available
  2. increase in thickness of the alveolar capillary exchange barrier
  3. increase in diffusion distance between the alveolar air space in the blood
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14
Q

factors affecting alveolar gas exchange
4. Adequate perfusion of
the alveoli

A

how good
is the blood capillary
network

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15
Q

how much of O2 in blood is transported as bound hemoglobin

A

98%

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16
Q

how much of O2 is transported as dissolved in blood plasma

A

2%

17
Q

one hemoglobin molecule has the potential to bind to

A

4 oxygen molecules

18
Q

Hemoglobin bound to oxygen is called

A

oxyhemoglobin (HbO2)

19
Q

The absolute
concentration of
dissolved gases also
depends on?

A

the solubility, ⍺, of oxygen
in water

20
Q

factors affecting alveolar gas exchange
3. gas diffusion between the blood and air

A
  • surface area
    -diffusion distance
  • barrier permeability
  • concentration gradient
21
Q

what gives red blood cells their color

A

hemoglobin

22
Q

3 ways carbon dioxide is transported

A
  1. cellular respiration (exhaled)
  2. to much CO2 can alter pH
  3. to much CO2 can depress CNS function and lead to death
23
Q

elevated CO2

A

hypercapnia

24
Q

pH disturbance by to much CO2

A

acidosis

25
Q

how much CO2 is dissolved in plasma

A

7%

26
Q

how much CO2 diffuses into red blood cells

A

93%

27
Q

what is it called when CO2 binds to hemoglobin

A

carbaminohemogolbin

28
Q

in RBC how much CO2 binds to hemoglobin

A

23%

29
Q

in RBC how much CO2 is converted to bicarbonate ions and goes into the plasma

A

70%

30
Q

steps of the first mechanism to remove free H+ and CHCO3

A
  1. bicarbonate leaves RBC on anitport protein
  2. chloride shift - HCO3 for Cl-
  3. ( the anion exchange keeps the cells electrical neutrality)
  4. transfer into plasma makes buffer available to moderate pH changes
31
Q

what is the most important extracellular buffer in the body

A

biocarbonate

32
Q

steps of the 2nd mechanism to act as intracellular buffer to maintain pH

A
  1. removes free from the red blood cell cytoplasm
33
Q

If blood is elevated much above normal, the hemoglobin buffer cannot soak up all the produced from the reaction of and water. In those cases, excess accumulates in the plasma, causing the condition known as?

A

respiratory acidosis

34
Q
A