Erectile Dysfunction

Question 1

What are the two types of erectile tissue?

Answer 1

Corpus cavernosa
Corpus spongiosum

Question 2

What does normal erection rely on?

Answer 2

Intact autonomic and somatic nerve supply to the penis
Arterial blood flow supplied by the paired cavernosal arteries
Smooth and striated musculature of the corpora cavernosa and pelvic floor

Question 3

How is erection caused and maintained?

Answer 3

Increase in arterial flow
Active relaxation of the smooth muscle within the sinusoids of the corpora cavernosa
Increase in venous resistance

Nitric oxide is a key neurotransmitter that initiates and sustains erections

Question 4

What is the pathophysiology of erectile dysfunction?

Answer 4

Consistent inability to attain or maintain a sufficiently rigid penile erection for sexual performance.

Question 5

What can organic ED be an early sign of?

Answer 5

Cardiovascular disease

Question 6

What is peyronie?

Answer 6

Fibrotic disorder of the tunica albuginea of the penis resulting in pin, curvature, or deformity.

Question 7

What causes anejaculation?

Answer 7

Androgen deficiency by decreasing prostate and seminal vesicle secretions

Question 8

When must free testosterone be tested?

Answer 8

8-10AM

Question 9

What treatments can be used for ED?

Answer 9

Phosphodiasterase 5 inhibitors
Tadalafil 2.5mg PO daily
Prn 10mg PO at least 30 min prior to sex
Avanafil 50-200mg PO, 15 min prior

Question 10

What are some of the complications?

Answer 10

MEDEVAC a priapism which is an erection lasting longer than 4 hours