Acid-Base Balamce In The Body Flashcards

1
Q

What is a major homeostatic challenge?

A

Keeping hydrogen levels of body in the appropriate range.

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2
Q

What type of diet produce more acid than bases and tend to acidify the blood?

A

High protein diet

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3
Q

What is the pH of systemic arterial blood?

A

7.35 and 7.45

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4
Q

What three major mechanisms that regulates removal of hydrogen?

A

Buffer systems
Exhalation of carbon dioxide
Kidney excretion of hydrogen into the urine

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5
Q

What substances act quickly to temporarily bind H+, removing the highly reactive, excess H+ from solution but not from the body?

A

Buffers

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6
Q

What buffer systems maintain pH?

A

Protein buffer system
Carbonic acid-bicarbonate buffer system
Phosphate buffer system

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7
Q

What is the most abundant buffer in ICF and Plasma?

A

Proteins

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8
Q

What does the carboxyl group work on?

A

Releases hydrogen when pH rises and reacts with excess OH-.

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9
Q

Can proteins buffer both acids and bases?

A

Yes

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10
Q

HCO3 acts as what?

A

Weak base

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11
Q

H2CO3 acts as what?

A

Weak acid

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12
Q

Where are the concentrations of phosphates highest in?

A

ICF which makes them an important buffer in the cytosol

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13
Q

At what range is arterial blood considered acidosis?

A

Less than 7.35 and under 7 is fatal

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14
Q

At what range is arterial blood considered alkalosis?

A

Greater than 7.45 which leads to muscle spasm

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