Epithelium Flashcards
Epithelial tissue
Covers the body surface/ lines body cavities
Avascular
Derive nutrients via diffusion from blood vessels in the underlying CT
What is the function of epithelial tissue cells in the intestine?
Absorption
What is the function of epithelial tissue cells in glands?
Secretion
What is the function of epithelial tissue cells in the skin?
Protection
What is the function of epithelial tissue cells in the neuroepithelium?
Sensory
What is the function of epithelial tissue cells in the myoepithelial?
Contractility
Basement Membrane
Separates the epithelial tissue from CT
Basal lamina, collagen, glycoproteins and heparin sulphate form the BM
PAS-positive and seen with LM
How can you classify epithelium?
Simple, stratified, and pseudostratified
Simple Epithelium
All cells life on the basal lamina
3 types: squamous, cuboidal and columnar
Stratified Epithelium
Has more than one layer and cell on the bottom layer lie on the basal lamina
4 types of stratified: squamous cuboidal, columnar and transitional
Pseudostratified
All cells lie on the basal lamina but appear stratified because their nuclei are in different locations
What can change the epithelium from one type to another?
A continuous abrasion or irritation.
Ex: stratified squamous non-keratinized to keratinized in the esophagus when milk diet is replaced by roughage in young animals
Or
Pathological change
Ex: pseudo-stratified columnar to stratified squamous in respiratory tract because of continuous smoke inhalation (metaplasia)
What is the most prevalent epithelium?
stratified squamous (keratinized or nonkeratinized)
How often is epithelia replaced?
Continuously replaced but the rate of replacement is variable
Microvilli
1 micrometer high and 80 nm wide
Function: increase the surface area of absorptive cells (intestine and kidney) by 15-40 times
ABSORPTION
Brush border
Microvilli grouped together, individual microvilli cannot be seen under the LM
AKA striated border
Stereocilia
10- 20 um
Long immotile microvilli
Present in the epididymus
Function: absorb testicular fluid
Cilia
Hair like processes 7-10um high, 0.2 um diameter
Consists of 2 central microtubules and 9 peripheral microtubule pairs
Function: moving cells and fluid past the cells
What does each peripheral microtubule pair have?
2 little dynein arms and a motor protein that used energy from ATP to hook up the next pair of microtubules
Kartagener Syndrome (Immotile Cilia Syndrome)
When a patient genetically lacks dynein arms
They’re infertile
More prone to respiratory syndrome