Epithelial Tissue Flashcards
Epithelial tissue cells
Aggregated polyhedral cells
Small amount of extracellular matrix
Connective tissue cells
Several types of fixed and wandering cells
Abundant amount of extracellular matrix
Muscle tissue cells
Elongated contractile cells
Moderate amount of extracellular matrix
Nervous tissue cells
Elongated cells with extremely fine processes
Very small amount of extracellular matrix
Epithelial tissue function
Lining of surface or body cavities; glandular secretion
Connective tissue function
Support and protection of tissues/organs
Muscle tissue function
Strong contraction; body movements
Nervous tissue function
Transmission of nerve impulses
General Function of Cytoskeleton
Structural: Structural support to cell; stabilizes junctions between cells
Movement: Assists in cytosol streaming and cell motility
Tight Junction
Cytoskeletal components: Actin filaments encircling the entire cell
Functions: Seals adjacent cells to one another, controlling passage of molecules between them; separates apical and basolateral membrane domains
(6-pack rings)
Adherent Junction
Cytoskeletal components: Actin filaments located right beneath tight junction
Functions: Provides points linking the cytoskeletons of adjacent cells; strengthens and stabilizes nearby tight junctions
(6-pack rings)
Desmosome
Cytoskeletal components: Intermediate filaments
Functions: Provides points of strong intermediate filament coupling between adjacent cells, strengthening their tissue
(Spot weld)
Hemidesmosome
Cytoskeletal components: Intermediate filaments
Functions: Anchors cytoskeleton to the basal lamina (basement membrane)
(Spot weld)
Gap Junction
Cytoskeletal components: None
Functions: Allows direct transfer of small molecules and ions from one cell to another as a way to communicate
Simple Squamous
Function: Facilitates the movement of the viscera (mesothelium), active transport by pinocytosis, secretion of biologically active molecules
Examples: Lining of vessels (endothelium); Serous lining of cavities: pericardium, pleura, peritoneum (mesothelium)
Simple Cuboidal
Function: Covering and secretion
Example: Covering the ovary, thyroid
Simple Columnar
Function: Protection, lubrication, absorption, secretion
Example: Lining of intestine, gallbladder
Stratified Squamous keratinized (dry)
Function: Protection; prevents water loss
Example: Epidermis
Stratified Squamous nonkeratinized (moist)
Function: Protection; secretion; prevents water loss
Example: Mouth, esophagus, larynx, vagina, anal canal
Stratified Cuboidal
Function: Protection; secretion
Example: Sweat glands, developing ovarian follicles
Stratified Transitional
Function: Protection, distensibility (the capacity to swell as a result of pressure from inside)
Example: Bladder, uterus, renal calyces
Stratified Columnar
Function: Protection
Example: Conjunctiva
Pseudostratified
Function: Protection, secretion; cilia-mediated transport of particles trapped in mucus out of the air passages
Examples: Lining of trachea, bronchi, nasal cavity
Goblet cells
unicellular glands that are simply scattered secretory cells.
Simple Glands
Exocrine glands with ducts that do not branch
Simple Tubular, Branched Tubular, Coiled Tubular, Acinar (or Alveolar), Branched Acinar
Compound Glands
Exocrine glands with ducts from several secretory units that converge into larger ducts
Tubular, Acinar, Tubuloacinar
Simple Tubular
A class of simple exocrine glands with elongated secretory portion; duct usually short or absent
Examples: Mucous glands of colon, intestinal glands or crypts
Branched Tubular
A class of simple exocrine glands with several long secretory parts joining to drain into one duct.
Coiled Tubular
A class of simple exocrine glands where the secretory portion is very long and coiled
Example: Sweat glands
Acinar or Alveolar (Simple)
A class of simple exocrine glands that have a rounded, saclike secretory portion
Branched Acinar
A class of simple exocrine glands with multiple saclike secretory parts entering the same duct
Example: Sebaceous glands of the skin
Tubular
A class of compound exocrine glands with several elongated coiled secretory units and their ducts converge to form larger ducts
Acinar or Alveolar (Compound)
A class of compound exocrine glands that have several saclike secretory units with small ducts converging at a larger duct
Example: Exocrine pancreas
Tubuloacinar
A class of compound exocrine glands that have ducts of both tubular and acinar secretory units that converge at larger ducts
Example: Salivary glands
Mechanisms of exocrine gland secretion
Merocrine, Holocrine, and Apocrine
Holocrine glands
Exocrine glands where cells disintegrate and the contents become secretion; involves cell disruption; involved in common form of acne
Example: Sebaceous gland of hair follicle
Apocrine glands
Exocrine glands where the apical portion of secretory cell is pinched off and secreted
Example: Mammary gland
Merocrine glands
Most common exocrine glands secretion where secretory vessels release contents by exocytosis; exocrine glands with merocrine secretion are either serous or mucous according to their secretory products, which give distinct staining to the cells.
Example: Salivary glands
Serous cells
synthesize proteins such as digestive enzymes, that are not glycosylated proteins
Filled apically with secretory granules
Well-developed RER and Golgi complexes.
Mucous cells (e.g., goblet cells)
Glycosylated proteins* (=glycoproteins) called
mucins.
Well-developed RER and Golgi complexes.
Lots of secretory granules
Absorption
the process of transport from an organ or duct’s lumen to capillaries near the epithelial basement membrane.
Secretion
Involves transport in the other direction from the
capillaries into a lumen, as in many glands. Secretion by epithelial cells removes water from the neighboring interstitial fluid or plasma and releases it as part of the specialized aqueous fluids in such organs.
What causes acne?
Excessive secretion of the sebaceous glands.
Serous and mucous glands have which type(s) of product secretion?
Both are merocrine.
What separates the sheet of epithelial cells from other tissues?
Basement membrane
Serous glands produce mostly
Non-glycosylated proteins
Which type of secretion do sebaceous glands have?
Holocrine
Loss of the microvilli of absorptive cells in the small intestine may be caused by
Gluten-sensitive enteropathy
What are two changes in respiratory tract cells associated with chronic bronchitis?
Increase in number of goblet cells and conversion of ciliated pseudostratified epithelium into stratified squamous epithelium
Given the structure of a cilium, you would not expect to find cilia on which of these types of epithelial tissue?
Stratified squamous keratinized epithelium
Stereocilia
Stereocilia are less common on tissues than cilia are, they are not actively motile, and they are longer than microvilli.
Move cells and fluids along a tube
A major difference between exocrine and endocrine glands is that
Exocrine glands have ducts and endocrine glands do not.
Endothelium is a type of epithelial tissue that lines the inner surface of blood vessels, and regulates passage of substances into the tissue below. Endothelium is composed of cells with what type of arrangement and shape?
Simple squamous
Which type of molecule are epithelial cell junctions made of?
Proteins
In some types of food poisoning, the toxin secreted by Clostridium perfringens binds proteins associated with ________________, and causes loss of tissue fluid into the intestinal lumen.
Tight junctions
Mucus is formed by hydrated mucins, which in turn are glycosylated proteins. What is glycosylation?
The process of adding a polysaccharide to another molecule such as a protein or lipid.
Which of these is a diagnostic or necessary characteristic of simple epithelium?
It is composed of a single cell layer.
The simple and compound gland types are distinguished according to what criterion?
Whether or not the ducts branch
Features of urothelium
It is distensible, it has a layer of umbrella cells, it lines much of the urinary tract
Where is stratified cuboidal epithelium found?
Excretory ducts of salivary and sweat glands.
Reversed prompt
Aggregated polyhedral cells
Small amount of extracellular matrix
Epithelial tissue cells
Reversed prompt
Several types of fixed and wandering cells
Abundant amount of extracellular matrix
Connective tissue cells
Reversed prompt
Elongated contractile cells
Moderate amount of extracellular matrix
Muscle tissue cells
Reversed prompt
Elongated cells with extremely fine processes
Very small amount of extracellular matrix
Nervous tissue cells
Reversed prompt
Lining of surface or body cavities; glandular secretion
Epithelial tissue function
Reversed prompt
Support and protection of tissues/organs
Connective tissue function
Reversed prompt
Strong contraction; body movements
Muscle tissue function
Reversed prompt
Transmission of nerve impulses
Nervous tissue function
Reversed prompt
Structural: Structural support to cell; stabilizes junctions between cells
Movement: Assists in cytosol streaming and cell motility
General Function of Cytoskeleton
Reversed prompt
Cytoskeletal components: Actin filaments encircling the entire cell
Functions: Seals adjacent cells to one another, controlling passage of molecules between them; separates apical and basolateral membrane domains
(6-pack rings)
Tight Junction
Reversed prompt
Cytoskeletal components: Actin filaments located right beneath tight junction
Functions: Provides points linking the cytoskeletons of adjacent cells; strengthens and stabilizes nearby tight junctions
(6-pack rings)
Adherent Junction
Reversed prompt
Cytoskeletal components: Intermediate filaments
Functions: Provides points of strong intermediate filament coupling between adjacent cells, strengthening their tissue
(Spot weld)
Desmosome
Reversed prompt
Cytoskeletal components: Intermediate filaments
Functions: Anchors cytoskeleton to the basal lamina (basement membrane)
(Spot weld)
Hemidesmosome
Reversed prompt
Cytoskeletal components: None
Functions: Allows direct transfer of small molecules and ions from one cell to another as a way to communicate
Gap Junction
Reversed prompt
Function: Facilitates the movement of the viscera (mesothelium), active transport by pinocytosis, secretion of biologically active molecules
Examples: Lining of vessels (endothelium); Serous lining of cavities: pericardium, pleura, peritoneum (mesothelium)
Simple Squamous
Reversed prompt
Function: Covering and secretion
Example: Covering the ovary, thyroid
Simple Cuboidal
Reversed prompt
Function: Protection, lubrication, absorption, secretion
Example: Lining of intestine, gallbladder
Simple Columnar
Reversed prompt
Function: Protection; prevents water loss
Example: Epidermis
Stratified Squamous keratinized (dry)
Reversed prompt
Function: Protection; secretion; prevents water loss
Example: Mouth, esophagus, larynx, vagina, anal canal
Stratified Squamous nonkeratinized (moist)
Reversed prompt
Function: Protection; secretion
Example: Sweat glands, developing ovarian follicles
Stratified Cuboidal
Reversed prompt
Function: Protection, distensibility (the capacity to swell as a result of pressure from inside)
Example: Bladder, uterus, renal calyces
Stratified Transitional
Reversed prompt
Function: Protection
Example: Conjunctiva
Stratified Columnar
Reversed prompt
Function: Protection, secretion; cilia-mediated transport of particles trapped in mucus out of the air passages
Examples: Lining of trachea, bronchi, nasal cavity
Pseudostratified
Reversed prompt
unicellular glands that are simply scattered secretory cells.
Goblet cells
Reversed prompt
Exocrine glands with ducts that do not branch
Simple Tubular, Branched Tubular, Coiled Tubular, Acinar (or Alveolar), Branched Acinar
Simple Glands
Reversed prompt
Exocrine glands with ducts from several secretory units that converge into larger ducts
Tubular, Acinar, Tubuloacinar
Compound Glands
Reversed prompt
A class of simple exocrine glands with elongated secretory portion; duct usually short or absent
Examples: Mucous glands of colon, intestinal glands or crypts
Simple Tubular
Reversed prompt
A class of simple exocrine glands with several long secretory parts joining to drain into one duct.
Branched Tubular
Reversed prompt
A class of simple exocrine glands where the secretory portion is very long and coiled
Example: Sweat glands
Coiled Tubular
Reversed prompt
A class of simple exocrine glands that have a rounded, saclike secretory portion
Acinar or Alveolar (Simple)
Reversed prompt
A class of simple exocrine glands with multiple saclike secretory parts entering the same duct
Example: Sebaceous glands of the skin
Branched Acinar
Reversed prompt
A class of compound exocrine glands with several elongated coiled secretory units and their ducts converge to form larger ducts
Tubular
Reversed prompt
A class of compound exocrine glands that have several saclike secretory units with small ducts converging at a larger duct
Example: Exocrine pancreas
Acinar or Alveolar (Compound)
Reversed prompt
A class of compound exocrine glands that have ducts of both tubular and acinar secretory units that converge at larger ducts
Example: Salivary glands
Tubuloacinar
Reversed prompt
Merocrine, Holocrine, and Apocrine
Mechanisms of exocrine gland secretion
Reversed prompt
Exocrine glands where cells disintegrate and the contents become secretion; involves cell disruption; involved in common form of acne
Example: Sebaceous gland of hair follicle
Holocrine glands
Reversed prompt
Exocrine glands where the apical portion of secretory cell is pinched off and secreted
Example: Mammary gland
Apocrine glands
Reversed prompt
Most common exocrine glands secretion where secretory vessels release contents by exocytosis; exocrine glands with merocrine secretion are either serous or mucous according to their secretory products, which give distinct staining to the cells.
Example: Salivary glands
Merocrine glands
Reversed prompt
synthesize proteins such as digestive enzymes, that are not glycosylated proteins
Filled apically with secretory granules
Well-developed RER and Golgi complexes.
Serous cells
Reversed prompt
Glycosylated proteins* (=glycoproteins) called
mucins.
Well-developed RER and Golgi complexes.
Lots of secretory granules
Mucous cells (e.g., goblet cells)
Reversed prompt
the process of transport from an organ or duct’s lumen to capillaries near the epithelial basement membrane.
Absorption
Reversed prompt
Involves transport in the other direction from the
capillaries into a lumen, as in many glands. Secretion by epithelial cells removes water from the neighboring interstitial fluid or plasma and releases it as part of the specialized aqueous fluids in such organs.
Secretion
Reversed prompt
Stereocilia are less common on tissues than cilia are, they are not actively motile, and they are longer than microvilli.
Move cells and fluids along a tube
Stereocilia
Reversed prompt
It is distensible, it has a layer of umbrella cells, it lines much of the urinary tract
Features of urothelium