Adipose Tissue Flashcards

1
Q

Adipocytes

A
the characteristic cells of 
adipose tissue (fat), These very large cells 
are derived from mesenchyme (a loose connective tissue).
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2
Q

Reticular fibers

A

support adipose tissue

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3
Q

Subcutaneous fat

A

A majority of fat that is found under the skin, for thermoregulation

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4
Q

Visceral fat

A

Fat found around certain organs, in bone marrow, between muscles, and in breast tissue. For cushioning organs such as the heart, gonads, kidneys, and intestines.

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5
Q

Two types of adipose tissue

A

Brown fat and white fat

Develop from preadipocytes

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6
Q

White Adipose

A

Produce the hormone leptin which helps inhibit hunger

Single huge lipid droplet

Fewer mitochondria

Subcutaneous and visceral
locations

Stores energy

Fewer capillaries

Fibroblasts and macrophages

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7
Q

Brown Adipose

A

Brown fat is localized to kidneys, adrenal glands, and a few other places.

Newborns have 2–5% of body weight in brown
fat, but this decreases through childhood.

The cells are brown because of the large
number of mitochondria and small lipid droplets.

Produces heat by “nonshivering thermogenesis.”

Many smaller lipid droplets

More mitochondria

Kidneys, adrenal glands, and a few other
places

More capillaries

Fibroblasts and macrophages

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8
Q

What three sources do white adipocytes store lipid from?

A
Dietary fats (including triglyerides and cholesterol) 
packaged as chylomicrons (a type of lipoprotein). 

• Other triglycerides produced in the liver and
circulating as very-low-density lipoproteins
(VLDLs).

• Fatty acids produced locally by breakdown of the
dietary fats and triglycerides by lipoprotein lipase.

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9
Q

How are lipids mobilized from adipocytes?

A

by the enzyme lipase that is activated primarily by the
hormone norepinephrine released from the
adrenal gland.

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10
Q

Lipids

A
  • Triglycerides (with fatty acids)
  • Cholesterol
  • Phospholipids

• These are transported through the body in
packages or particles called lipoproteins.

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11
Q

Triglyceride

A

glycerol + three fatty acid chains

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12
Q

Lipoprotein function

A

a biochemical assembly whose primary function is to transport fat molecules in water, as in blood plasma or other extracellular fluids, where they are taken into cells by endocytosis.

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13
Q

Lipoprotein composition

A

They are composed of
phospholipids, triglycerides,
proteins, and cholesterol.

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14
Q

Lipoprotein classification

A

They are classified by their density.
• ULDL (ultralow-density, largest (= chylomicrons)
• VLDL (very-low density)
• IDL (Intermediate density)
• LDL (Low density)*
• HDL (High density, smallest)*

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15
Q

Chylomicrons (ULDLs)

A

transport dietary lipids from the intestines to
other locations in the body, where the triglycerides are broken down by the enzyme lipase.

one of the five major
groups of lipoproteins (sorted by density) that enable fats and cholesterol to move within the water
-based solution of the bloodstream

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16
Q

Obesity

A

excessive adipose tissue accumulation. More fat is accumulated in the cells; the number of fat cells does not increase.

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17
Q

Lipid storage

A

Free fatty acids + glycerol -> Triglyceride droplet

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18
Q

Lipid mobilization

A

Norepinephrine + Lipase -> Fatty acids + glycerol

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19
Q

What is the main function of brown adipose tissue?

A

Thermogenesis

20
Q

In routine histological sections, why is it not possible to see the lipid in the fat cells?

A

The solvents used to prepare the slides dissolve the lipid.

21
Q

A benign fat cell tumor is called a

22
Q

Which type of fibers form the supporting framework of white adipose tissue?

A

Reticular fibers

23
Q

Norepinephrine stimulates a lipase that breaks down triglycerides into

A

Glycerol and fatty acids

24
Q

Functions of adipose tissue

A

Energy storage
Cushioning organs
Thermogenesis
Insulation

25
Which type of fat is less common in the body?
Brown fat is less common (by weight) in the body than white fat.
26
# Reversed prompt ``` the characteristic cells of adipose tissue (fat), These very large cells are derived from mesenchyme (a loose connective tissue). ```
Adipocytes
27
# Reversed prompt support adipose tissue
Reticular fibers
28
# Reversed prompt A majority of fat that is found under the skin, for thermoregulation
Subcutaneous fat
29
# Reversed prompt Fat found around certain organs, in bone marrow, between muscles, and in breast tissue. For cushioning organs such as the heart, gonads, kidneys, and intestines.
Visceral fat
30
# Reversed prompt Brown fat and white fat Develop from preadipocytes
Two types of adipose tissue
31
# Reversed prompt Produce the hormone leptin which helps inhibit hunger Single huge lipid droplet Fewer mitochondria Subcutaneous and visceral locations Stores energy Fewer capillaries Fibroblasts and macrophages
White Adipose
32
# Reversed prompt Brown fat is localized to kidneys, adrenal glands, and a few other places. Newborns have 2–5% of body weight in brown fat, but this decreases through childhood. The cells are brown because of the large number of mitochondria and small lipid droplets. Produces heat by "nonshivering thermogenesis." Many smaller lipid droplets More mitochondria Kidneys, adrenal glands, and a few other places More capillaries Fibroblasts and macrophages
Brown Adipose
33
# Reversed prompt ``` Dietary fats (including triglyerides and cholesterol) packaged as chylomicrons (a type of lipoprotein). ``` • Other triglycerides produced in the liver and circulating as very-low-density lipoproteins (VLDLs). • Fatty acids produced locally by breakdown of the dietary fats and triglycerides by lipoprotein lipase.
What three sources do white adipocytes store lipid from?
34
# Reversed prompt by the enzyme lipase that is activated primarily by the hormone norepinephrine released from the adrenal gland.
How are lipids mobilized from adipocytes?
35
# Reversed prompt * Triglycerides (with fatty acids) * Cholesterol * Phospholipids • These are transported through the body in packages or particles called lipoproteins.
Lipids
36
# Reversed prompt glycerol + three fatty acid chains
Triglyceride
37
# Reversed prompt a biochemical assembly whose primary function is to transport fat molecules in water, as in blood plasma or other extracellular fluids, where they are taken into cells by endocytosis.
Lipoprotein function
38
# Reversed prompt They are composed of phospholipids, triglycerides, proteins, and cholesterol.
Lipoprotein composition
39
# Reversed prompt They are classified by their density. • ULDL (ultralow-density, largest (= chylomicrons) • VLDL (very-low density) • IDL (Intermediate density) • LDL (Low density)\* • HDL (High density, smallest)\*
Lipoprotein classification
40
# Reversed prompt transport dietary lipids from the intestines to other locations in the body, where the triglycerides are broken down by the enzyme lipase. one of the five major groups of lipoproteins (sorted by density) that enable fats and cholesterol to move within the water -based solution of the bloodstream
Chylomicrons (ULDLs)
41
# Reversed prompt excessive adipose tissue accumulation. More fat is accumulated in the cells; the number of fat cells does not increase.
Obesity
42
# Reversed prompt Free fatty acids + glycerol -\> Triglyceride droplet
Lipid storage
43
# Reversed prompt Norepinephrine + Lipase -\> Fatty acids + glycerol
Lipid mobilization
44
# Reversed prompt Energy storage Cushioning organs Thermogenesis Insulation
Functions of adipose tissue
45
The storage droplets in a fat cell contain:
Triglycerides
46
The particles formed from ingested triglycerides, phospholipids, and cholesterol are called
Chylomicrons
47
Hydrolysis of VLDLs in the blood capillaries forms
Free fatty acids