Epithelial cells Flashcards

1
Q

Epithelial cell cancer?

A

Carcinoma.

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2
Q

Neural cell cancer?

A

Neuroblastoma.

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3
Q

Glial cell cancer?

A

Glioma

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4
Q

Epithelial tissue architecture?

A

Organised, continuous and cohesive layers of cells.

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5
Q

What is the classification of epithelial cells shape?

A

Squamous (flattened) , cuboidal and columnar.

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6
Q

What is the classification of epithelial cells layering?

A

Simple (single layer) and stratified (multi-layer).

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7
Q

Where may you find simple squamous epithelium?

A

Lung alveolar. Thin allows short diffusion path.

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8
Q

Where may you find simple cuboidal epithelium?

A

Ducts such as kidney ducts.

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9
Q

Where may you find simple columnar epithelium?

A

Found in surfaces involved in absorption and secretion such as enterocytes.

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10
Q

What are the two types of stratified squamous epithelium? Can you explain the two types.

A

Keratinising and non keratinising. Keratinising produce keratin and die but become strong protective structures. Non keratinising don’t die and so retain nuclei and organelles.

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11
Q

What is pseudostratified epithelium?

A

Epithelial cells which seem to be arranged in layers but have surface cells that are attached to basal lamina.

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12
Q

What is apical domain?

A

The domain of the epithelial cell that faces the lumen or environment.

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13
Q

What is basolateral domain?

A

The domain of epithelial cell that mediates attachment to underlying tissue. Faces ECM

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14
Q

In transporting epithelium how is the basal membrane adapted?

A

Membrane infolds result in greater surface area to pump molecules across basal membrane. Mitochondria for active transport.

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15
Q

What kind of transport occurs at apical domain?

A

Passive transport with ion channels while on basolateral domain active transport occurs. This ensures directionality.

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16
Q

3 types of epithelium for movement of molecules?

A

Transportive, secretory and absorption.

17
Q

2 types of secretory epithelium?

A

Exocrine (secretion from apical plasma membrane) and endocrine (secretion from basal lateral surface).

18
Q

How are epithelial cells replaced?

A

Proliferation of stem cells.

19
Q

How do chemotherapy drugs damage intestinal epithelium?

A

Inhibition of the proliferation of stem cells in intestinal crypts results in loss of intestinal villi and flattening of intestinal mucosa.

20
Q

What virus results in hyperproliferation of epithelial cells?

A

Papilloma virus.