EOM: IMMS Flashcards

1
Q

What are microtubules made up of?

A

Tubulin

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2
Q

Describe what happens during anaphase.

A
  • Chromosomes move towards opposite poles

- There is no nuclear membrane

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3
Q

What type of epithelium is found in the walls of the vagina?

A

Non-keratinised stratified squamous

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4
Q

What type of epithelium is found in the pleural cavity?

A

Squamous mesothelium

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5
Q

What type of epithelium is found in the trachea?

A

Pseudostratified ciliated columnar interspersed with goblet cells

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6
Q

What type of epithelium is found in the duodenum and small intestine?

A

Simple columnar

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7
Q

What type of epithelium is found in the ureter?

A

Urothelium - a mix of pseudostratified and stratified (described as having an umbrella), non-keratinised and can stretch.

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8
Q

Where is ciliated epithelia found?

A

Respiratory tract and fallopian tubes

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9
Q

Define a supersecondary structure.

A

A combination of secondary structures (often consist of combinations of alpha and beta structures) e.g. zinc finger, helix-turn-helix.

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10
Q

Define locus heterogeneity.

A

Mutations of various genes that give the same clinical condition e.g. hypertrophic cardiomyopathy

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11
Q

Define allelic heterogeneity.

A

Also known as heterogeneity, when many mutations in one gene cause a condition so all individuals with the disease have the same mutations e.g. cystic fibrosis

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12
Q

Define allelic polymorphism.

A

When more than one allele can be found for a given gene within the normal population

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13
Q

What are the components of cell membranes?

A
  • Cholesterol
  • Glycolipids
  • Lipoproteins
  • Phospholipids
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14
Q

Which enzyme catalyses 1,3-biphosphoglycerate to 3-phosphoglycerate in aerobic glycolysis?

A

Phosphoglycerate kinase

Note: kinase means “enzyme that moves phosphate”

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15
Q

Give the name of 4 enzymes used in both an- and aerobic respiration.

A
  • Aldolase
  • Hexokinase
  • Phosphoglucose isomerase
  • Triose phosphate isomerase
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16
Q

How many kcal are there in one unit of alcohol?

A

56 kcal

  • 7 kcal per gram
  • 10 ml in a unit = 8 grams
17
Q

Define basal metabolic rate.

A

Amount of energy expended at complete rest

  • Hypothyroidism lowers BMR
  • Hyperthyroidism increases BMR
18
Q

What is the role of ATP synthase in oxidative phosphorylation?

A

Transports protons into the mitochondrial matrix.

19
Q

What proportion of body water is found in the plasma?

A

7%

20
Q

How is cholesterol transported into cells?

A

Facilitated diffusion via receptor-mediated endocytosis