EOM: CARDIO Flashcards

1
Q

The heart is supplied by:

A

Left and right coronary arteries

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2
Q

The left coronary artery divides into:

A

Left anterior descending, left marginal and circumflex arteries

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3
Q

Compared to other veins (35%), O2 saturation in coronary venous blood is very low. Why?

A

Oxygen extraction by cardiac muscle is much higher compared to other cells.

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4
Q

What does the right coronary artery supply?

A

The inferior surface of the heart - right ventricle, right atrium, SAN and AVN

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5
Q

The right coronary artery divides into:

A

Right marginal and posterior interventricular (80/85%) arteries

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6
Q

What does the left coronary artery supply?

A

Left atrium and left ventricle

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7
Q

When does blood flow to the myocardium occur?

A

Mainly during diastole

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8
Q

What organ is responsible for the synthesis of coagulation factors and fibrinogen?

A

Liver

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9
Q

What is the precursor for an enzymes that lyses clots?

A

Plasminogen ( –> plasmin, which breaks down fibrin into fibrin degradation products)

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10
Q

What makes up the coagulation cascade?

A

A series of proteolytic enzymes that circulate in plasma in an inactive form, and generate thrombin when activated.
- Thrombin then catalyses the conversion of fibrinogen I (soluble) to fibrin (insoluble)

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11
Q

What is the role of platelet dense granules?

A

Released upon cell activation, contain a high concentration of a molecule which acts as an agonist at the platelet P2Y12 receptor i.e. binds to it and activates it.

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12
Q

What is responsible for the apex beat and where is it palpated?

A

Left ventricle - normally palpated in the left 5th intercostal space and midclavicular line.

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13
Q

What prevents backflow of blood into the left atrium during ventricular systole?

A

Mitral valve

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14
Q

What is the function of the aortic valve?

A

Maintains systemic diastolic blood pressure by preventing backflow of blood into the heart during diastole.

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15
Q

What represents ventricular repolarisation?

A

T wave

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16
Q

What is the normal duration for the PR interval?

A
  1. 12 - 0.2 milliseconds
    - Period that extends from the beginning of the P wave (=onset of atrial depolarisation) to the beginning of the QRS complex
17
Q

What assesses the electrical activity within the lateral myocardial territory?

A

Leads I, aVL, V5 and V6

18
Q

Which lead yields complexes normally inverted compared to anterior and inferior leads?

A

aVR

19
Q

What happens to the ST segment during acute injury/infarction of a substantial myocardial territory?

A

Abnormal elevation (the larger the elevation, the more severe the problem)

20
Q

What does the QRS complex represent?

A

Ventricular depolarisaion

- Should last less than 0.12 milliseconds