Enzymes that make neurotransmitters for the brain-------------------END--------------------- Flashcards

1
Q

for the brain, what are the important amino acids?

A

glutamic acid, GABA, Glycine

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2
Q

for the brain, what are the important monoamines?

A

acetylcholine, serotonin, histamine

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3
Q

for the brain, what are the important catecholamines?

A

Dopamine, Norepinephrine, Epinephrine

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4
Q

what enzyme synthesizes GABA?

A

glutamic acid decarboxylase, converts Glutamic Acid to GABA

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5
Q

what enzyme produces Acetylcholine?

A

choline acetyltransferase form choline and acetyltransferase

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6
Q

how is 5-HTP (5-hydroxytryptamine) or serotonin produced?

A

tryptophan to 5-hydroxytryptophan via tryptophan hydroxlase (rate limiting step) then that 5-hydroxytryptophan converted to 5-hydroxytryptamine via 5-hydroxytryptophan decarboxylase

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7
Q

how is histamine produced, by what enzyme?

A

histidine decarboxylase

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8
Q

what is the rate limiting step in the production of norepinephrine?

A

tyrosine hydroxylase

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9
Q

what enzyme produces Dopamine?

A

amino acid decarboxylase from DOPA

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10
Q

what enzyme produces norepinephrine?

A

dopamine beta hydroxylase from dopamine

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11
Q

where is epinephrine made? what important enzyme makes this? is this a hormone or NT?

A

in the adrenal medulla; PNMT (phenylethanolamine-N-methyltransferase); hormone

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