18 - Limbic Systems Flashcards

1
Q

what are the structures of the limbic system and their function?

A

olfactory cortex
hippocampal formation
amygdala
hypothalamus

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2
Q

what is the function of the olfactory cortex?

A

olfaction

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3
Q

what is the function of the hippocampal formation?

A

memory

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4
Q

what is the function of the amygdala?

A

emotion and drives

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5
Q

what is the function of the hypothalamus?

A

homeostasis; autonomic and neuroendocrine control

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6
Q

what does the primary olfactory cortex receive direct input from?

A

the secondary sensory neurons without an intervening thalamic relay

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7
Q

under the olfactory system, the anterior entorhinal cortex receives projections from the _____?

A

piriform cortex

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8
Q

under the olfactory system, how does the piriform cortex project to the orbitofrontal olfactory area?

A

directly and indirectly via relays in the entorhinal cortex or in the mediodorsal nucleus of the thalamus

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9
Q

what is the hippocampal formation comprised of?

A

dentate gyrus
hippocampus
subiculum

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10
Q

in terms of the hippocampal formation, what is the dentate gyrus comprised of (three layers)?

A

moving inward from the pia, the molecular layer, granule layer, and polymorphic layer

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11
Q

in terms of the hippocampal formation, what are the principal neurons of the dentate gyrus?

A

granule cells

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12
Q

in terms of the hippocampal formation, what are the layers of the hippocampus and the subiculum?

A

same for both they are molecular layer, pyramidal layer, polymorphic layer

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13
Q

in terms of the hippocampus formation, the principal neurons of the hippocampus and subiculum are the _____?

A

pyramidal cells

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14
Q

what is the importance of the circuit of papez from the hippocampal formation?

A

for the cortical control of emotion and long term memory storage

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15
Q

an important output is the projection from the _____ to the _____?

A

subiculum to the entorhinal cortex; an additional output pathway is the fornix which carries the outputs to the diencephalon and septal nuclei

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16
Q

what are the important structures we learned associated with memory and the parahippocampal gyrus?

A

medial temporal lobe
medial diencephalic
basal forebrain

17
Q

what is the medial temporal lobe (MTL)?

A

hippocampal formation and adjacent cortex of the parahippocampal gyrus

Communicates with the association cortex via the entorhinal cortex

18
Q

what is the medial diencephalic memory areas (MD)?

A

Thalamic mediodorsal nucleus, anterior nucleus of the thalamus, internal medullary lamina, mammillary bodies, and other diencephalic nuclei lining the third ventricle

communicates with the MTL through several unnamed systems

19
Q

what is the basal forebrain?

A

Also plays a role in memory (primarily through its widespread cholinergic projections to cerebral cortex)

20
Q

what is declarative memory? name an example?

A

Involves conscious recollection of facts or experiences

amnesia (anterograde and retrograde)

21
Q

what is amnesia?

A

a type of declarative memory loss typical of bilateral MTL or bilateral MD lesions

22
Q

what is anterograde amnesia?

A

Deficit in forming new memories

23
Q

what is retrograde amnesia?

A

Loss of memories from a period of time before the brain injury

24
Q

what is non declarative memory?

A

Involves nonconscious learning of skills, habits, and other acquired behaviors

25
Q

where is the amygdala located?

A

a group of nuclei located in the anteromedial temporal lobe

26
Q

what are the three main nuclei of the amygdala?

A

basolateral nuclei
corticomedial nuclei
central nuclei

27
Q

what is the function of the basolateral nuclei?

A

Connections to diverse cortical areas, basal forebrain, medial thalamus

28
Q

what is the function of the corticomedial nuclei?

A

Olfaction, hypothalamus related appetite

29
Q

what is the function of the central nuclei?

A

Autonomic control

30
Q

what is the amygdala important for?

A

attaching emotional significance to various stimuli perceived by the association cortex

31
Q

what is the activity of the amygdala important for?

A

fear, anxiety, and aggression, whereas, activity in the septal area is important in pleasurable states

32
Q

both side ablation of amygdala causes?

A

placid behavior

33
Q

Reciprocal connections between the amygdala and hypothalamic and brainstem centers for autonomic control mediate changes?

A

heart rate, peristalsis, gastric secretion, piloerection, sweating, etc., changes commonly seen with strong emotions

34
Q

describe the reward center of the amygdala?

A

these are located along the course of the medial forebrain bundle, especially in the lateral and ventromedial nuclei of the hypothalamus

35
Q

describe the punishment center of the amygdala?

A

found in the central gray area surrounding the aqueduct of Sylvius in the mesencephalon and extending upward into the periventricular zones of the hypothalamus and thalamus.

36
Q

what are the three nuclei that comprise the amygdala?

A

corticomedial, basolateral, and central nuclei

37
Q

this structure is important for memory?

A

Parahippocampal cortex