Enzymes

Question 1

Are all cofactors required for enzyme activity?

Answer 1

All apart from co-enzymes

Question 2

What are the three types of cofactors?

Answer 2

Inorganic cofactors, co-enzymes, prosthetic groups

Question 3

Where are inorganic cofactors obtained from?

Answer 3

via the diet as minerals usually ions

Question 4

Do inorganic cofactors bind temporarily or permanently?

Answer 4

may be either as may bind temporarily or may be a permanent part of an enzyme

Question 5

Where are co-enzymes derived from?

Answer 5

vitamins, organic molecules

Question 6

Do co-enzymes bind temporarily or permanently to an enzyme?

Answer 6

temporarily

Question 7

What is the role of a co-enzyme?

Answer 7

transfer substances between molecules to increase the rate of reaction/enzyme activity

Question 8

Do prosthetic groups bind permanently or temporarily to an enzyme?

Answer 8

permanently bound to an enzyme to form a permanent feature of an enzyme

Question 9

How may inorganic cofactors and prosthetic groups increase an enzyme’s rate of activity?

Answer 9

• they change the shape/tertiary structure of the active site
• they may affect the charges of the active site
• they could bind to or interact with the substrate

Question 10

An enzyme’s active site is a specific shape created by which level of protein structure?

Answer 10

tertiary

Question 11

Is catalase an intracellular or extracellular enzyme?

Answer 11

intracellular

Question 12

Is trypsin an intracellular or extracellular enzyme?

Answer 12

extracellular

Question 13

What is the cofactor for carbonic anhydrase?

Answer 13

Zn2+