Endocrine System Flashcards

1
Q

What is the function of the endocrine system?

A

Manufacture, storage and release of hormones

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2
Q

The endocrine system is involved in regulating? (4)

A

Metabolism
Growth
Reproductive functions
Body’s stress response

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3
Q

Hormone levels are usually maintained by?

A

Negative feedback

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4
Q

Functioning endocrine gland tumour may cause?

A

Hyposecretion or Hypersecretion

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5
Q

What are the main endocrine glands in the cranial cavity?

A

Hypotahlamus

Pituitary gland

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6
Q

What are the main endocrine glands in the neck?

A

4 parathyroid glands

Thyroid gland

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7
Q

What are the main endocrine glands in the abdomen?

A

2 adrenal glands

Pancreas

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8
Q

What are the main endocrine glands in the pelvis?

A

2 ovaries - females

2 testes - males

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9
Q

What makes up the diencephalon?

A

Thalamus and hypothalamus

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10
Q

Where is the diencephalon located?

A

Central core of the cerebrum

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11
Q

The pituitary gland is n extension of the? What connects them?

A

Hypothalamus

Infundibulum

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12
Q

The pituitary gland is divided into which lobes?

A

Anterior and posterior

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13
Q

What is also known as the neurohypophysis?

A

The posterior pituitary gland

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14
Q

Axons from the hypothalamus project through the _____– to the posterior pituitary

A

infundibulum

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15
Q

What does the posterior pituitary gland manufacture?

A

Oxytocin and ADH (aka vasopressin)

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16
Q

Where are oxytocin and ADH produced?

A

In the soma (nucleus) of the posterior pituitary gland

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17
Q

What is the function of oxytocin?

A

Allows social bonding
Women sense movement of breast milk from breast to nipple
Stimulates contraction in uterus

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18
Q

What transports oxytocin and ADH from the soma to the axoplasm in the post. pituitary gland?

A

Axoplasmic (neurosecretory) transport

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19
Q

What are the two types of hormones that the hypothalamic neurone secrete?

A

Releasing

Release-inhibitory hormones

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20
Q

Releasing hormones from the hypothalamus stimulate?

A

Anterior pituitary gland to release its hormone(s) into the bloodstream

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21
Q

Release-inhibitory hormones form the hypothalamus prevent?

A

Anterior pituitary gland from releasing hormone(s)

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22
Q

What does the anterior pituitary gland secrete?

A
Growth hormone
Prolactin
TSH
Adrenocorticotrophic hormone (ACTH - effect on adrenal glands) 
Lutenising hormone 
FSH
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23
Q

The anterior pituitary gland secretes its hormones into the SVC via?

A

The hypophyseal veins

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24
Q

What is a portal system?

A

Two venous capillary beds joined by a portal vein

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25
The thyroid gland uses iodine to manufacture?
Triiodothyronine (T3) and thyroxine (T4)
26
What do the thyroid hormones regulate?
Metabolism and stimulate growth
27
The 4 parathyroid glands manufacture and secrete?
The parathyroid hormone (PTH)
28
How is PTH release controlled?
Gland monitors and responds to blood Ca2+ directly
29
What does the PTH control?
Calcium in the blood and bone
30
Besides bone and blood, what depends on calcium control?
Nerve function
31
Whatere are the parathyroid glands located?
In the posterior aspect of the larynx and trachea
32
Which branches of the aorta supply the thyroid and parathyroid glands?
Right inferior thyroid arteries | Left thyroid artery (comes off the common carotid artery)
33
What is the venous drainage of the thyroid and parathyroid glands?
Right superior, middle and inferior thyroid veins into the SVC
34
Where is the pancreas located?
Retroperitoneal overlying the L1 and L2 vertebrae
35
What are the anatomical relations of the pancreas?
Post. to the stomach Anterior to IVC and SVC Between duodenum and spleen
36
What is the arterial blood supply to the pancreas?
Coeliac trunk and superior mesenteric artery
37
Venous blood from the pancreas drains into?
Splenic vein, superior mesenteric vein | Then into the hepatic portal vein
38
Where are the adrenal glands?
Retroperitoneal on top of the kidneys
39
What separates the adrenal glands from the kidneys?
Fascial septum
40
What are the 2 anatomical parts of the adrenal glands?
Adrenal cortex | Adrenal medulla
41
What does the adrenal cortex secrete?
Glucocosteroids Mineralocorticoids Androgens
42
What is the effect of gluco-costeroids?
Influence metabolic rates of protein, fats, sugars (cortisol)
43
Gluco-costeroids are under _____ control?
Pituitary
44
What is the effect of mineralocorticoids?
Regulate salt balance and impact on blood volume/pressure
45
What are androgens?
Male sex hormone
46
What does the adrenal medulla secrete?
Adrenaline/noradrenaline (Fight/Flight Volume)
47
The fight/flight response results from fear, serious illness or injury and results in the sympathetic division of the ANS causing the adrenal medulla to?
Adrenal medulla secretes adrenaline/noradrenaline into blood stream
48
What is the arterial supply of the adrenal glands?
Left and right superior, middle and inferior suprarenal artery
49
What is the venous drainage of the adrenal glands?
Right suprarenal vein - drains into IVC directly | Left suprarenal vein (drains into left renal vein)
50
Where are the testes located?
In the scrotum of the male perineum
51
What is the blood supply to the tests/ovaries?
Gonadal arteries and veins
52
The testes secrete? In response to?
Testosterone | In response to LH from the pituitary gland
53
What does testosterone control?
Male secondary sexual characteristics Closure of epiphyseal growth plates Stimulates sperm
54
Where are the ovaries located?
In broad ligament of female pelvis
55
What do the ovaries secrete?
Oestrogen and progesterone
56
Ovaries secrete oestrogen and progesterone in response to?
FSH and LH from the anterior pituitary gland
57
Progesterone prepares uterus for?
Pregnancy
58
Oestrogen controls?
Female secondary sex characteristics and ovum development
59
The gonadal arteries are paired branches of the ?
Abdominal aorta
60
The right gonadal vein drains into ?
The IVC
61
The left gonadal vein drain into?
Left renal vein