Endocrine System Flashcards
Hormones
Chemical messengers
Circulate in the blood
Act upon specific target cells
Bring about specific changes in cellular function
Exocrine glands
Glandular portion - lines with secretory epithelial cells
Duct portion - lines with simple cuboidal or columnar epithelial cells
Exocrine glands function
Secrete non-hormone products via ducts to a target organ, body cavity or tissue surface
Endocrine glands
Ductless
Hollow spherical follicles lines with secretory epithelial cells
Each follicle is surrounded by an extensive capillary network
Endocrine glands function
Produce hormones that are secreted into interstitial fluid and diffused into the blood where it travels to the target organ, tissue or cell
Functions
Co-ordination
Homeostasis
Glandular secretion
Metabolism
Behaviour
Growth and development
Physical appearance
Reproduction
Digestion
Circadian rhythm
Body fluids
Immune response
Mood and emotions
Hunger
Hypothalamus
Anterior region of the brain
Below thalamus
Above brainstem
Neurosecretory cell bodies
Hypothalamus - function
Co-ordinating homeostatic mechanisms, behaviour patterns and neuroendocrine outputs
Regulates - temperature, fluid volume, growth, pain and pleasure response, hunger and thirst
Hypothalamus - releasing and inhibiting hormones
Corticotropin (CRH) - releasing hormone
Thyrotropin (TRH) - releasing hormone
Growth hormone (GH) - releasing hormone
Gonadotropin - releasing hormone
Somatostatin - inhibiting GH and thyroid stimulating hormone (TSH)
Pituitary gland
Small pea-shaped gland
Lies at the base of the brain within the pituitary fossa of the sphenoid bone
Suspended from hypothalamus by the infundibulum
Anterior and posterior lobes
Pituitary gland - function
Anterior - endocrine organ
Posterior - endocrine organ and nervous functions, intrinsically connected to the hypothalamus
Pituitary gland - anterior pituitary gland
75% total weight
Two parts - pars tuberalis and pard distalis
Mass of endocrine glandular epithelial cells forming continuous cords around sinusoid capillary network
Pituitary gland - hormones released by anterior pituitary gland
Thyroid-stimulating hormone (TSH) - thyroid hormone synthesis
Adreno-corticotropic hormone (ACTH) - secretion of glucocorticoid hormones
Melanocyte-stimulating hormone (MSH) - influence brain activity
Human growth hormone (HGH) - growth and repair, lipid, carbs and protein metabolism
Follicle-stimulating hormone (FSH) - oestrogen, sperm production
Luteinizing hormone (LH) - progesterone, testosterone
Prolactin (PRL) - milk production and secretion
Pituitary gland - posterior pituitary gland
Includes the infundibulum and the pard nervous
Pituitary gland - hormones released by posterior pituitary gland
Oxytocin (OT) - uterine contractions, milk release
Antidiuretic hormone (ADH) - reduces urine output