Endocrine System Flashcards

1
Q

Endocrine system

A

Regulates bodily function & maintains homeostasis through network of organs that communicate directives to various tissues

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2
Q

Eustress

A

Positive, desirable form of stress; increased: neural efficiency, vascular compliance, O2 extraction, cardiac function, musculoskeletal integrity & function

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3
Q

Distress

A

Negative form of stress; increased: platelet adhesion, cortisol production, LDL & triglycerides, susceptibility to inflammation, loss of protein sparing

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4
Q

Role of hormones

A

Released by endocrine glands to direct actions of other tissues via chemical messenger

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5
Q

Steroid hormones

A

Cholesterol based compounds impact sexual development, reproduction, tissue synthesis, inflammation, metabolism (cortisol, estrogen, testosterone)

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6
Q

Polypeptide hormones

A

Chains of amino acids synthesized within endocrine cells, activate secondary messengers (insulin, glucagon)

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7
Q

Pituitary Gland

A

Releases growth hormone

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8
Q

Thyroid

A

Releases thyroxine

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9
Q

Adrenal Cortex

A

Releases aldosterone, cortisol

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10
Q

Growth Hormone Action

A

Stimulates IGF, protein synthesis, growth & metabolism

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11
Q

Thyroxine Action

A

Stimulates metabolic rate, regulates cell growth & activity

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12
Q

Aldosterone Action

A

Promotes sodium, potassium metabolism & water retention

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13
Q

Cortisol Action

A

Promotes use of fatty acids and protein catabolism, conserves sugar, maintains blood glucose

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14
Q

Adrenal Medulla

A

Releases epinephrine, norepinephrine

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15
Q

Epinephrine action

A

Increases cardiac output, increases glycogen catabolism and fatty acid release

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16
Q

Norepinephrine action

A

Properties of epinephrine, constricts blood vessels

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17
Q

Pancreas

A

Releases insulin, glucagon

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18
Q

Insulin action

A

Promotes cellular glucose uptake, stores glycogen, aids in protein synthesis

19
Q

Glucagon action

A

Releases sugar from liver into blood circulation

20
Q

Liver

A

Releases insulin like growth factors

21
Q

IGF action

A

Increases protein synthesis

22
Q

Ovaries

A

Release estrogen

23
Q

Estrogen action

A

Stimulates bone remodeling activity; female sex hormone

24
Q

Testes

A

Release testosterone

25
Testosterone action
Stimulates growth, increases protein anabolism, reduces body fat; male sex hormone
26
Anabolic hormones
Compounds involved in tissue growth and protein synthesis
27
Growth hormone
Promotes cell division by facilitating protein synthesis; mobilizes lipids for fuel, protecting glycogen stores
28
IGF1
Central signalling hormone for muscle growth following resistance training
29
Testosterone
Anabolic hormone in men and woman; stimulates male secondary sex characteristics in men and acts on gene expression of protein synthesis; men have 10x women
30
Estrogen
Steroid hormone integral to bone health in men and women; promotes secondary sex characteristics in women; men convert to estradiol
31
Carbohydrates are metabolized into glucose to
Regulate blood sugar levels
32
Pancreas has two main functions
Produce digestive enzymes to break down macronutrients for absorption in lining of small intestine; regulate blood sugar levels through release of insulin and glucagon
33
Hyperglycemia
Abnormally high blood glucose levels; can damage bodily tissues including vascular structures (diabetes)
34
Hypoglycemia
Abnormally low blood glucose levels; metabolic demands of brain and CNS can't be met
35
Glucagon
Stimulates glycogen breakdown in liver to increase blood glucose levels
36
Insulin
Pulls blood glucose into tissue; dysfunction associated with insulin resistance and diabetes
37
Thyroid
Primary regulator of growth and metabolism rate; acts via T3 & T4
38
Hypothyroidism
Low thyroid activity; results in weight gain, can retard growth & mental development
39
Catecholamines
Potent neurotransmitters that help the body respond to stress or elicit fight/flight response (dopamine, epinephrine, norepinephrine)
40
Cortisol
Released in response to exercise stress and low glucose levels; chronic elevation associated with overtraining
41
Fight or flight response
Acute increase in adrenal activity; enhanced CO, blood flow, energy metabolism in response to perceived threat
42
Adrenal glands are very important to managing
Exercise based stress response
43
Hormone response to anaerobic training
Increased: GH, T3/T4, cortisol & epinephrine (heavy only), testosterone Decreased: Insulin
44
Hormone response to aerobic training
High intensity (above lactate threshold) increases GH Testosterone suppressed in high intensity training Higher insulin sensitivity, glucagon when prolonged Steady catecholamines Increased cortisol when prolonged Does not stimulate GH-IGF pathways