endocrine dz Flashcards
what glands are most commonly affected in small animals
thyroid, adrenal, pancreas, parathyroid, testes, ovaries
usually endocrine disease occurs when one or more of the endocrine glands….. (3 things)
work ineffectively, work incorrectly, dont work at all
____ is the active form of thyroid hormone
triiodothronine
affects dogs more than cats
hypothyroid
affects cats more than dogs
hyperthyroid
clinical signs include: wt gain, bilaterally symmetrical alopecia, cold intolerant, skin infections, repro problems
hypothyroid
insufficient thyroid hormone
hypothyroidism
surplus of thyroid hormone
hyperthyroidism
clinical signs include: wt loss, voracious appetite, vomiting, tachycardia +/- murmur, aggressive behavior, hyperactivity
hyperthyroid
tx: levothyroxine
hypothyroid
tx: methimazole
hyperthyroid
radioactive iodine 131 tx
hyperthyroid
insulin is produced in the __ cells of the pancreas while glucagon is produced in the __cells
beta, alpha
what does serum fructose concentration (fructosamine) measure
average blood sugar concentration over time
what does DKA stand for
diabetic ketoacidosis
during DKA, the animal begins to break down its own ___ stores for energy. this leads to the production of ___. there are 3 types of ketones: ____,____,___
fat ; ketones ; acetoacetate, b-hydroxybutyrate, acetone
ketones have a negative affect on ____
perfusion, bp, CO, homeostasis
what is a plantigrade stance
walking flatfooted in the hind end, walking on hocks
what laboratory finding might be found in a patient with DM
hyperglycemia, glucosuria, high BG
what are signs of insulin overdose
weakness, incoordination, seizures, ataxia, coma
what are 3 causes of insulin related hypoglycemia
too high dose of insulin, not feeding the pet with insulin, increased exercise, wt loss
what are symptoms of pancreatitis
vomiting, diarrhea, anorexia, painful abdomen
what is an insulinoma
tumor of beta cells of the pancreas
what species is commonly affected by insulinomas
ferrets