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BSN LAST TEST-Pt 2 > Endocrine: ADH, TPH, SIADH, and DI > Flashcards

Endocrine: ADH, TPH, SIADH, and DI Flashcards

1
Q

ADH

What does this target?

A

Kidney tubules, collecting ducts –> controls permeability to water and water reabsorption

Arterial wall smooth muscle–> vasoconstriction

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2
Q

TPH-Discharge instructions

Report what?

A

Any post nasal drip or increased swallowing, which ma indicate CSF leak

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3
Q

TPH-Discharge instructions

What is the halo sign?

A

Light yellow color at edge of clear drainage that indicates CSF

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4
Q

TPH-Discharge instructions

HOB position?

A

Elevated

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5
Q

TPH-Discharge instructions

Avoid what?

A

Activities that raise ICP

*cough, sneeze, blow nose, brush teeth, tie shoe, bend at waist

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6
Q

TPH-Discharge instructions

If pt. can’t brush teeth then what do they do to keep mouth clean?

A

Dental floss, mouth rinse, lub jelly to lips

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7
Q

TPH-Discharge instructions

Decreased sense of smell is normal or abnormal?

A

Normal

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8
Q

TPH-Discharge instructions

What will the be on the rest of their life?

A

Vasopressing

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9
Q

TPH-Discharge instructions

Mouth or nose breathing?

A

MOUTH ONLY!

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10
Q

SIADH

Drug tx?

A
  • Furosemide
  • Phenytoin
  • Demeclocycline
  • Conivaptin and tolvaptin (vasopressin receptor antagonist)
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11
Q

SIADH

What does furosemide do?

A

Gets rid of water

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12
Q

SIADH

Why give phenytoin?

A

Inhibits release of ADH

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13
Q

SIADH

What does demeclocycline do?

A

Decreases renal tubule response to ADH so more water is excreted

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14
Q

SIADH

Who gets vasopressin receptor antagonists?

A

When hyponatremia present in hospitalized pts

*promotes water excretion w/o Na loss

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15
Q

SIADH

Examples of vasopressin receptor antagonists?

A

Conivaptin

Tolvaptan

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16
Q

SIADH

What is BBW with tolvaptan?

A

Rapid increase in serum sodium levels that can cause comp;actions death

If used for more than 30 days at high dose can cause liver failure and death

17
Q

DI

ADH replacement or excretion?

A

Replacement

18
Q

DI

What is the ADH replacement drug?

A

DDAVP (desmopressin acetate)

*give orally or intranassaly in metered spray

19
Q

DI

DDAVP for mild issues?

A

1-2 sprays in 24 hr period

20
Q

DI

DDAVP for severe?

A

2 doses 2-3x/d in 24 hr period

21
Q

DI

SE of DDAVP nasal spray?

A

Ulceration of MM
Allergy
Sensation of tightening of chest
Lung inhalation

  • if SE or URI occur, then oral or sq vasopressin would be given
  • in severe, ADH would be given IM or IV
22
Q

DI

What other drugs can be given beside DDAVP?

A

Vasopressin
ADH stimulants
Thiazide diuretic

23
Q

DI–Nephrogenic

What drugs?

A

Thiazide diuretic

Amiloride

BSN LAST TEST-Pt 2 (22 decks)

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