Embryology Flashcards
Alar Plate
Dorsal, Sensory
Basal Plate
Ventral, Motor
Notochord
Nucleus Pulposus and IV disc in adults, Induces overlying ectoderm to differentiate into neuroectoderm and formneural plate
Neural Plate
Neural Tube and Neural Crest Cells
Prosencephalon
Forebrain, makes up the telencephalon and diencephalon
Telencephalon
Cerebral hemispheres and lateral ventricles
Diencephalon
Thalamus and third ventricle
Mesencephalon
Midbrain, aqueduct
Rhombencephalon
hindbrain, splits into metencephalon & myelencephalon
Metencephalon
Pons and cerebellum
upper part of 4th ventricle
Myelencephalon
medulla, lower part of 4th ventricle
Neuroectoderm
CNS neurons, ependymal cells, oligodendroglia, astrocytes
Neural Crest
PNS neurons, Schwann cells
Mesoderm
Microglia
Neural Tube Defects
elevated AFP in amniotic fluid and maternal serum, increased AChE in amniotic fluid
Failure of bony spinal canal to close but no structural herniation. Tuft of hair or skin dimple at level of bony defect
Spina bifida occulta
Meninges, not spinal cord, herniate through spinal canal defect (normal AFP)
Meningocele
Meninges and spinal cord herniate through spinal canal defect
Meningomyelocele
Malformation of anterior neural tube resulting in no forebrain, polyhydraminos
Anencephaly
Frog-like appearance
Anencephaly