Childhood Primary Brain Tumors

Question 1

Tumor most often found in posterior fossa, GFAP (+)

Answer 1

Pilocytic astrocytoma

Question 2

Rosenthal fibers

Answer 2

Eosinophilic, corkscrew fibers

Pilocytic astrocytoma

Question 3

“drop metastases” of spinal cord

Answer 3

Medulloblastoma

Question 4

Primitive neuroectoderm that can compress 4th ventricle

Answer 4

Medulloblastoma

Question 5

Homer-Wright rosettes, small blue cells

Answer 5

Medulloblastoma

Question 6

Perivascular rosettes

Answer 6

Ependymoma

Question 7

Rod-shaped blepharoplasts

Answer 7

basal ciliary bodies found near nucleus, ependymoma

Question 8

Ependymal cell tumors most commonly found in 4th ventricle

Answer 8

ependymoma

Question 9

Remnant of Rathke Pouch

Answer 9

Craniopharyngioma

Question 10

Most common childhood supratentorial tumor

Answer 10

Craniopharyngioma

Question 11

Cingulate (subfalcine) herniation under flax cerebri

Answer 11

Compress anterior cerebral artery

Question 12

Uncal herniation

Answer 12

medial temporal lobe compresses on IL CNIII, blown pupil, “down-and-out” gaze, IL PCA (CL homonymous hemianopsia)

Question 13

CL crus cerebri

Answer 13

IL paralysis, “false localization” sign

Question 14

Cerebellar tonsilar herniation

Answer 14

coma and death