Anatomy and Physiology Flashcards
Locus Ceruleus (pons)
Norepinephrine
Ventral tegmentum and SNc (midbrain)
Dopamine
Raphe nucleus (pons, medulla, midbrain)
5-HT
Basal Nucleus of Meynert
ACh
Nucleus Accumbens
GABA
Anxiety NTs
Increased NE
Decreased 5-HT & GABA
Depression NTs
Decreased in NE, DA, 5-HT
Huntington NTs
Increased in DA
Decreased in ACh and GABA
Parkinson NTs
Increased in 5-HT, ACh
Decreased in Dopamine
Alzheimer NTs
Decreased in ACh
Nucleus accumbens and septal nucleus
Reward center, pleasure, addiction, fear
3 Structures in BBB
Tight Junctions b/w nonfenestrated capillary endothelial cells, basement membrane, astrocyte foot processes
Area Postrema
Vomiting after chemo
OVLT
osmotic sensing
Lateral Area of Hypothalamus
Hunger
Destruction = Anorexia, failure to thrive
Ventromedial Area of Hypothalamus
Satiety
Destruction = hyperphagia