Anatomy and Physiology Flashcards

1
Q

Locus Ceruleus (pons)

A

Norepinephrine

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2
Q

Ventral tegmentum and SNc (midbrain)

A

Dopamine

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3
Q

Raphe nucleus (pons, medulla, midbrain)

A

5-HT

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4
Q

Basal Nucleus of Meynert

A

ACh

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5
Q

Nucleus Accumbens

A

GABA

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6
Q

Anxiety NTs

A

Increased NE

Decreased 5-HT & GABA

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7
Q

Depression NTs

A

Decreased in NE, DA, 5-HT

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8
Q

Huntington NTs

A

Increased in DA

Decreased in ACh and GABA

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9
Q

Parkinson NTs

A

Increased in 5-HT, ACh

Decreased in Dopamine

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10
Q

Alzheimer NTs

A

Decreased in ACh

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11
Q

Nucleus accumbens and septal nucleus

A

Reward center, pleasure, addiction, fear

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12
Q

3 Structures in BBB

A

Tight Junctions b/w nonfenestrated capillary endothelial cells, basement membrane, astrocyte foot processes

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13
Q

Area Postrema

A

Vomiting after chemo

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14
Q

OVLT

A

osmotic sensing

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15
Q

Lateral Area of Hypothalamus

A

Hunger

Destruction = Anorexia, failure to thrive

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16
Q

Ventromedial Area of Hypothalamus

A

Satiety

Destruction = hyperphagia

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17
Q

Anterior Hypothalamus

A

Cooling, parasympathetic

Destruction = can’t cool down, too hot

18
Q

Posterior Hypothalamus

A

Heating, Sympathetic

Destruction = can’t heat up, too cold

19
Q

Suprachiasmatic Nucleus

A

Circadian Rhythm

20
Q

Tx of bedwetting

A

oral desmopressin acetate (DDAVP)

21
Q

Alcohol, Benzodiazepines and barbituates effect on sleep

A

decreases REM and delta wave

22
Q

Extraocular movements during REM sleep

A

PPRF - paramedian pontine reticular formation

23
Q

Awake eyes open

A

Beta, highest frequency, lowest amplitude

24
Q

Awake eyes closed

A

Alpha

25
Q

Stage N1

A

Light sleep, theta waves

26
Q

Stage N2

A

Deeper sleep; when bruxism occurs

27
Q

Sleep Spindles and K complexes

A

Stage N2

28
Q

Stage N3

A

Deepest non-REM sleep; sleepwalking, night terrors, and bedwetting

29
Q

Delta Waves

A

Lowest frequency, highest amplitude, Stage N3

30
Q

REM sleep

A

Beta waves, Loss of motor tone, increased brain oxygen use and increased pulse and BP

31
Q

Supraoptic Nuclei

A

ADH

32
Q

Paraventricular Nuclei

A

Oxytocin

33
Q

VPL Nucleus of Thalamus

A

Pain and temperature; pressure, touch, vibration, and proprioception

34
Q

VPM Nucleus of Thalamus

A

Face sensation and taste

35
Q

LGN Nucleus of Thalamus

A

From CN II, Vision (Lateral, light)

36
Q

MGN Nucleus of Thalamus

A

From Superior olive and Inferior colliculus of tectum

Hearing (Medial, music)

37
Q

VL Nucleus of Thalamus

A

From Basal Ganglia; motor

38
Q

Limbic System Structures

A

Hippocampus, Amygdala, Fornix, Mammillary Bodies, and Cingulate Gyrus

39
Q

Lateral Lesions of Cerebellum

A

propensity to fall toward injured (IL) side

40
Q

Medial Lesions of Cerebellum

A

Vermal Cx, Fastigal nuclei and/or flocculonodular lobe
truncal ataxia, nystagmus, and head tilting
Wide-based cerebellar gait