Embryology Flashcards

1
Q

3 germ cells layer

A

Endoderm
Mesoderm
Ectoderm

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2
Q

The nervous system is derived from this germ layer

A

Ectoderm

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3
Q

Neural plate is formed during

A

3rd week

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4
Q

Name of longitudinal formation that appears in neural plates

A

Neural groove

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5
Q

These structures bound both sides of neural plate

A

Neural folds

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6
Q

How is the neural tube formed

A

The neural folds fuse which converts the neural groove into the neural tube

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7
Q

How is the neural crest formed

A

Lateral margin of neural plate do not get incorporated in neural tube and form a strip of ectodermal cells between the neural tube and covering ectoderm

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8
Q

What do neural crest differentiate into

A
Posterior roots ganglia 
sensory ganglia of cranial nerves
 Autonomic ganglia 
Cells of suprarenal medulla 
 melanocytes
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9
Q

What does the cephalic ends of the neural tube form after dilatation

A

Three primary brain vesicles
forebrain vesicles
midbrain vesicles
hidbrsin vesicle

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10
Q

What does the rest of the neural tube form after elongation

A

Spinal cord

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11
Q

When does myelin sheath start forming

A

Before birth and first year postnatally

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12
Q

What is the embryonic period

A

Period Up to ninth week of gestation

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13
Q

What is the fetal period

A

When external genitalia are distinguishable

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14
Q

At what time does the neural plate form

A

Third week of life fetal life

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15
Q

From what germ layer does the neural plate forms

A

The ectodermal surface

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16
Q

What structure are formed from the infolding of the neural plates

A

The neural tube

the neural crest

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17
Q

What does the neural tube form in the future

A

The central nervous system

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18
Q

What does the neural crest form in the future

A

The peripheral nervous system

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19
Q

What do the neuroectodermal cells differentiate into

A

Neurons e, astrocytes, oligodendrocytes, ependymal cells

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20
Q

What’s neurological sells there is derived from the mesoderm

A

Microglial cells

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21
Q

In what week of fetal life can you see the subdivisions of forebrain midbrain and Hindbrain , the dorsal and ventral horn of the spinal cord , and peripheral and sensory nerves

A

5th week

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22
Q

When does Myelinization begins and how long does it last

A

Midgestation and continues for years

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23
Q

When does myelinization of the cortex starts

A

7 to 8 months Gestation

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24
Q

What nutrients are required for myelinization to occur

A

Cholesterol

iron

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25
What week of gestation is the gross structure of the nervous system established
Eighth week
26
Why what month is the behavioral evidence of neural function detectable
The third month
27
Can physicist respond to external stimuli and if yes by what time
By the third trimester they respond to external stimuli by raising heart rates and having body movements
28
When do Fetuses open their eyes
By the seventh month
29
What are the primitive reflexes of fetuses
Palmar grasp Rooting Moro
30
What is the palmar grasp reflex
The infants fingers reflexively grasp an object placed into their palm
31
When does the palmar grasp start and how long does it last
By 32 week and last for 2 to 3 months
32
What is the rooting reflex
Baby turned ahead and opened her mouth to follow and routes in the direction of the stroking of their mouth so that they can breasts or bottle feed
33
When does the rooting reflex start and how long does it last
Starts at 36 weeks and last for 10 months
34
What is the Moro reflex
Baby spread their arms out Pulls their arms back in tight to the chest cry
35
When does the moro reflex start and how long does it last
37 week | Last for six months
36
What is the behavior pattern of a baby
``` 1 month - watches person 2 month - smile 4 month - lol 7 month - roll over, reach and grasp 10 months - sit with no support, responds to name, says mama dada , waves bye 1 yr - walks 2 yrs - walks up and down 18-24 months - Balance ,agility ,85% of adult head circumference ,object permanence ,cause-and-effect understood ```
37
What determines the growth and shape of skull
The brain
38
One month total brain percentage
36% of adult brain
39
One year total brain percentage
72% of adults brain
40
Two years total brain percentage
83% of adult brain
41
When do you complete 90% of your brain growth
By age 6 age 6
42
What is a fontanelle
Non ossified areas of newborn skull
43
What are the major fontanelles
Anterior | posterior
44
At what age does the posterior fontanelle close
2-6 month
45
At what time does the Anterior fontanelle close
By age 18 month
46
What can cause delayed closure of the anterior fontanelle
Increased intracranial pressure | hypothyroidism
47
What can cause premature closure of the anterior fontanelle
Craniosynostosis | hypophosphatemia
48
What is the most dramatic developments in the. 18 to 24 month
Speech development
49
What are the two components of language development
Receptive - auditory comprehension | expressive - speech and language production
50
What is adolescence
Period of concrete thinking of school age children to form a logical operations of adults they develop moral thinking’s parallels general cognitive development
51
What are some causes of dysfunction of the neuro system
``` Genetic Perinatal Medical psychologic environmental social cultural ```
52
What are some chromosomal abnormalities that leads to neurological dysfunction
Trisomies
53
What are the perinatal risk factors
``` Low birthweight severe intrauterine growth restriction birth asphyxia prenatal exposure to alcohol drugs lead teratogenesis ```
54
What are some learning disorder
Dyslexia dysgraphia spelling mathematics dyscalculia
55
Type of brain waves in infancy
Delta waves
56
Type of brain waves at 3 yearsold
Alpha waves
57
Type of brain waves at four years old
Beta waves
58
Type of brain waves Between four and eight years old
Theta waves
59
How do you measure the electrical activity of a brain
Electroencephalogram EEG
60
How does abnormal electrical activity of the brain manifest
TTonic clonic attack atonic attack( abscehces ) abnormal Posturing such as infantile spasms
61
What is cerebral palsy
Disorder of movement and posture due to dysfunction of the brain before age 2 years old
62
What are the clinical signs and symptoms of cerebral palsy
``` Spastic hemiplegia spastic diplegia spastic quadriplagia Choreoathetoid ataxic and mixed ```
63
What are the steps of the formation the brain and the spinal cord
``` Dorsal induction Ventral induction Neuronal proliferation Differentiation , histogenesis Neuronal migration Axonal myelination ```
64
What is dorsal induction
Formation of notochord, neural plate, neural groove, neural folds, neural tube
65
When does dorsal induction occur
Between week 4-7
66
What is primary neurulation in dorsal induction
Neural plate creases inward Edges come into contactand fuse Form future brain and spinal cord
67
What is secondary neurulation in dorsal induction
Hollowing process leading to formation of lower sacral and coccygeal cord
68
When does ventral induction occur
5-10 weeks
69
What is ventral induction
Formation of vesicles
70
What are the brain vesicles forned in ventral induction
Prosencephalon (Telencephalon , Diencephalon) mesencephalon Rhombencephalon (Metencephalon , Myelencephalon )