Embryology 1&2 Flashcards

1
Q

What is embryology?

A

Study of the embryo

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2
Q

Name the 3 phases of embryology

A

Pre-embryonic phase
embryonic phase
foetal phase

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3
Q

What weeks does the pre embryonic phase occur?

A

0-3

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4
Q

What weeks does the embryonic phase take place?

A

4-8 weeks

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5
Q

What weeks does the foetal phase take place?

A

9-40 weeks

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6
Q

What is a spermatogonium?

A

An early cell which will give rise to sperm and found in the gonads

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7
Q

What is an oogonium?

A

An early cell in the production of an ovum and is found in the gonads

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8
Q

How many sperm are formed in spermatogenesis?

A

4

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9
Q

How many ovum are produced in oogenesis?

A

1 and 3 polar bodies

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10
Q

Why can there not just be 1 sperm surrounding one ovum in fertilisation?

A

Must be 100’s of sperm surrounding the ovum to allow one to enter

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11
Q

Where does fertilisation occur?

A

Distal end of the uterine tube

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12
Q

What is the pro nucleus of a sperm and ovum?

A

The genetic material only

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13
Q

When the pro nucleus of the ovum and sperm fuse what is formed?

A

Zygote

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14
Q

What is a zygote?

A

The first cell

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15
Q

Is a zygote diploid or haploid?

A

diploid

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16
Q

Do you inherit your mitochondria from your mum or your dad?

A

Mum

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17
Q

When a zygote divides a solid ball of cells is formed. What is this called?

A

Morula

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18
Q

Give an example of a mitochondrial disease

A

Lebers hereditary neuropathy which leads to blindness

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19
Q

Why does a cavity develop when the morula keeps on increasing in size?

A

Getting nutrition to the central core is difficult

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20
Q

What are the cells that accumulate at one end called?

A

inner cell mass

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21
Q

What are the outer lining of cells called?

A

trophoblast

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22
Q

What is the structure arising from a morula called?

A

blastocyst

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23
Q

When does a blastocyst form?

A

Day 5-6

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24
Q

What is the main requirement for the blastocyst to be able to reach and implant in the uterus?

A

healthy ciliated epithelium

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25
Why does ectopic pregnancy occur?
The cilia are not functioning properly
26
What exact structure does the blastocyst bury into in the uterine wall?
endometrium
27
myometrium
the smooth muscle tissue of the uterus
28
endometrium
inner epithelial layer of the uterus
29
At around what day does the blastocyst bury into the endometrium?
about day 7
30
What allows the blastocyst to bury into the endometrium?
The chorion
31
What forms the chorion?
The trophoblast dividing into 2 layers of cells which forms the chorion
32
What are the finger like structures on the chorion called?
chorionic villi
33
Name the 3 things that the chorion does
implantation of blastocyst forms part of placenta Secretes HCG
34
What is HCG used for?
To detect pregnancy
35
Until what week does HCG increase until?
week 12
36
What des HCG do?
Maintain the endometrium
37
What is the decidua basalis?
Endometrium deep to implanted conceptus with maternal blood vessels
38
What do the cells of the inner cell mass form?
The bilaminar disc
39
What 2 compartments does the bilaminar disc seperate?
The amniotic cavity above and the yolk sac below
40
What are the two parts of the bilaminar disc called?
The epiblast and the hypoblast
41
By what week is the placenta matured by?
18-20 weeks
42
In comparison to the fetus how much does the placenta weigh?
1/6
43
State the 3 main functions of the placenta
Foetal nutrition Transport of waste and gases Immune properties
44
What are the 2 parts of the placenta?
The maternal part and the foetal part
45
Briefly describe the maternal part of the placenta
Decidua basalis of endometrium | Rough with maternal blood vessels
46
Briefly describe the foetal part of the placenta
Smooth with foetal blood vessels and end of umbilical cord
47
Name the 2 different types | Of twins
Fraternal and identical
48
Which type of twins can run in families?
Fraternal
49
What is the primitive streak?
Dipping in of cells of the epiblast - forms in the midline
50
Once the primitive streak is formed what is also formed?
The axis of the embryo
51
What is the term given to the formation of germ layers?
gastrulation
52
Name the 3 germ layers
ectoderm mesoderm endoderm
53
How is the notochord formed?
Cells from ectoderm sink down to form a solid tube
54
How are the germ layers formed?
epiblast cells migrate down and displace the hypoblast
55
What is the term given to the formation of the neural tube?
neurulation
56
What induces ectodermal cells in the midline to form a neural tube?
The notochord
57
What does the neural tube induce?
Mesoderm to thicken
58
Name the 3 parts the mesoderm separates into
paraxial mesoderm intermediate plate mesoderm lateral plate mesoderm
59
What does the lateral mesoderm split to give?
Somatic and splanchnic mesoderm
60
What does the paraxial mesoderm give rise to?
somites
61
What does the intermediate plate mesoderm give rise to?
Urogenital system (kidneys and reproduction)
62
What does the lateral plate mesoderm give rise to?
Body cavity and coverings
63
When do the lateral folds begin?
week 3
64
What day does the heart start to beat?
day 24
65
Where does the gut formation arise?
endoderm
66
How many pairs of somites form?
43
67
Name the 3 things that somites divide into
dermatome myotome sclerotome
68
Dermatome give rise to..?
dermis of skin
69
myotome give rise to...?
muscles
70
sclerotome give rise to...?
bones including vertebrate
71
What is teratology?
Study of when things go wrong during development
72
Teratogens
environmental factors that cause abnormal development
73
What causes congenital rubella syndrome?
contraction of german measles when pregnant
74
Give some examples of environmental teratogens
drugs alcohol viruses radiation
75
When is there a highest risk and sensitivity to teratogens?
week 3-8
76
Give some examples of prenatal tests to diagnose malformations
anomaly ultrasound scan - 12 weeks blood test amniocentesis and chorionic villus sampling
77
Give some examples of postnatal tests to diagnose malformations
hip stability fingers and toes hearing testes descent