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First Aid STEP 1 > Embryogeneses Genes > Flashcards

Embryogeneses Genes Flashcards

1
Q

Sonic hedgehog

A

Produced at base of limbs in zone of polarizing activity
Involved in patterning along anteroposterior axis and CNS development.
Mutation can cause holoprosencephaly (forebrain fails to develop into two hemispheres)

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2
Q

Wnt-7

A

Produced at apical ectodermal ridge (thickened ectoderm at distal end of developing limb)
Necessary for proper organization along dorsal-ventral axis

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3
Q

FGF

A

Prodced at apical ectodermal ridge

Stimulates mitosis of underlying mesoderm, provides lengthening of limbs

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4
Q

Homeobox (Hox)

A

Involved in segmental organization of embryo in a craniocaudal direction
Code for transcription factors
Hox mutations –> appendages in wrong location

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First Aid STEP 1 (21 decks)

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