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First Aid STEP 1 > Drug reactions (all systems here) > Flashcards

Drug reactions (all systems here) Flashcards

1
Q

Name the sulfa drugs

A 
Sulfonamide antibiotics
Sulfasalazine
Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonylureas

– Fever, UTI, SJS, hemolytic anemia, thrombocytopenia, agranulocytosis, urticaria

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2
Q

Coronary vasospasm 3

A

Cocaine
Sumatriptan
Ergot alkaloids

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3
Q

Cutaneous flushing 5VANCE

A 
Vancomycin
Adenosine
Niacin
Ca CB
Echinocandins
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4
Q

Dilated cardiomyopathy

A

Anthracyclines (doxorubicin, daunorubicin)

prevent with Dexrazoxane

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5
Q

Torsades de pointes

A 
AntiArrhythmics (IA, III)
AntiBiotics (macrolides)
AntiCychotics (haloperidol)
AntiDepressants (TCAs)
AntiEmetics (ondansetron)
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6
Q

Adrenocortical insufficiency

A

HPA suppression secondary to glucocorticoid withdrawal

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7
Q

Hot flashes

A

Tamoxifen

Clomiphene

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8
Q

Hyperglycemia

A 
Tacrolimus
Protease inhibitors
Niacin
HCTZ
Corticosteroids
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9
Q

Hypothyroidism

A

Lithium
Amiodarone
Sulfonamides

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10
Q

Acute cholestatic hepatitis (jaundice)

A

Erythromycin

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11
Q

Diarrhea

A 
Acamprosate
Acarbose
Cholinesterase inhibitor (inc ACh, inc parasympathetics)
Colchicine
Erythromycin
Ezetimibe
Metformin
Misoprostol
Orlistat
Pramlintine
Quinidine
SSRIs
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12
Q

Focal to massive hepatic necrosis

A

Halothane
Amanita phalloids (death cap mushrooms)
Valproid acid
Acetaminophen

Liver “HAVAc”

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13
Q

Hepatitis

A 
Rifampin
Isoniazid (anti TB, stops mycolic acid synthesis)
Pyrazinamide
Statis
Fibrates
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14
Q

Pancreatitis

A 
Didanosine
Corticosteroids
Alcohol
Valproid acid
Azathioprine
Diuretics (furosemine, HCTZ)

“Drugs Causing a Violent Abdominal Distress”

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15
Q

Pill-induced esophagitis

A

Tetracyclines
Bisphosphonates
Potassium chloride

  • Caustic effect minimized with upright posture and adequate water ingestion
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16
Q

Pseudomembranous colitis

A

Clindamycin
Ampicillin
Cephalosporin

  • abx predispose to superinfections by resistant C diff
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17
Q

Agranulocytosis

A 
Clozapine
Carbamazepine
Prophylthiouracil
Methimazole
Colchicine
Ganciclovir

“Can Cause Pretty Major Collapse of Granulocytes”

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18
Q

Aplastic anemia

A 
Carbamazepine
Methimazole
NSAIDs
Benzene
Chloramphenicol
Propylthiouracil

“Can’t Make New Blood Cell Properly”

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19
Q

Direct Coombs-positive hemolytic anemia

A

Methyldopa

Penicillin

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20
Q

Gray baby syndrome

A

Chloramphenicol

21
Q

Hemolysis in G6PD deficiency

A 
Isoniazid
Sulfonamides
Dapsone
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin

“Hemolysis IS D PAIN”

22
Q

MegaloBLASTic anemia

A

Phenytoin
Methotraxate
Sulfa drugs

“Having a BLAST with PMS”

23
Q

Thrombocytopenia

A

Heparin

24
Q

Thrombotic complications

A

OCPs

Hormone replacement therapy

25
Q

Fat redistribution

A

Protease inhibitors
Glucocorticoids

“Fat PiG”

26
Q

Gingival hyperplasia

A

Phenytoin
Ca CB
Cyclosporine

27
Q

Hyperuricemia (gout)

A 
Pyrazinamide
Thiazides
Furosemide
Niacin
Cyclosporine

“Painful Tophi and Feet Need Care”

28
Q

Myopathy

A 
Fibrates
Niacin
Colchicine
Hydroxychloroquine
Interferon alpha
Penicillamine
Statins
Glucocorticoids
29
Q

Osteoporosis

A

Corticosteroids

Heparin

30
Q

Photosensitivity

A

Sulfonamides
Amiodarone
Tetracyclines
5-FU

“STAT For Photo”

31
Q

Rash (SJS)

A

Anti-epileptic drugs (Lamotrigine)
Allopurinol
Sulfa drugs
Penicillin

“Steven Johnson has epileptic allergy to sulfa drugs and penicillin”

32
Q

SLE-like syndrome

A 
Sulfa drugs
Hydralazine
Isoniazid
Procainamide
Phenytoin
Etanercept

“Having lupus is SHIPPE”

33
Q

Teeth discoloration

A

Tetracyclines

34
Q

Tendonitis, tendon rupture and cartilage damage

A

Fluoroquinolones

35
Q

Cinchonism

A

Quinine, quinidine

36
Q

Parkinson-like syndrome

A

Antipsychotics
Reserpine
Metoclopramide

37
Q

Seizures

A 
Isoniazid (vit B6 def)
Bupropion
Imipenem/cilastatin
Tramadol
Enflurane
38
Q

Tardive dyskinesia

A

Antipsychotics

Metoclopramide

39
Q

Diabetes Insipidus

A

Lithium

Demeclocycline

40
Q

Fanconi syndrome

A

Tenofovir

Ifosfamide

41
Q

Hemorrhagic cystitis

A

Cyclophosphamide
Ifosfamide

Administer MESNA to prevent this

42
Q

Interstitial nephritis

A

Methicillin
NSAIDs
Furosemide

43
Q

SIADH

A

Carbamazepine
Cyclophosphamide
SSRIS

“Can’t Concentrate Serum Sodium”

44
Q

Dry cough

A

ACE inhibitors

45
Q

Pulmonary fibrosis

A 
Methotraxate
Nitrofurantoin
Carmustine
Bleomycin
Bisulfan
Amiodarone

“My Nose Cannot Breath Bad Air”

46
Q

Antimuscarinic (multiorgan)

A

Atropine
TCAs
H1 blocker
Antipsychotics

47
Q

Disulfiran-like rxn

A 
Metronidazole
Cephalosporins
Griseofulvin
Procabazine
1st gen sulfonylureas
48
Q

Nephrotoxic/Ototoxic

A

Aminoglycosides
Vancomycin
Loop diuretics
Cisplatin (respond to amifostine)

First Aid STEP 1 (21 decks)

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